Jie Huang | Biological Sciences | Best Researcher Award

Dr. Jie Huang | Biological Sciences | Best Researcher Award

University of Oxford | United Kingdom

Dr. Jie Huang (黄杰), is a distinguished plant biologist currently serving as a postdoctoral researcher at the Department of Biology, University of Oxford. His research focuses on molecular plant–pathogen interactions, alternative splicing, and effector biology. Dr. Huang has made substantial contributions to our understanding of how pathogens manipulate plant immune responses and has published widely in high-impact journals.

Professional profile👤

Google Scholar

Strengths for the Awards✨

1. Strong Academic Background & Training

  • PhD from Nanjing Agricultural University under a leading expert, Prof. Suomeng Dong.

  • Postdoctoral experience at the prestigious University of Oxford, a global hub for biological sciences.

2. Consistent and High-Impact Research Output

  • Multiple first-author and corresponding-author publications in top-tier journals such as Nature Communications, Advanced Science, The Plant Cell, Molecular Plant, and New Phytologist.

  • His research appears in elite plant biology and molecular journals, indicating significant peer recognition and impact.

3. Innovation in Research

  • Pioneered discoveries related to alternative splicing in plant immunity, plant-pathogen interactions, and protein-peptide interactions, a critical frontier in molecular plant pathology.

  • Integration of computational tools (AlphaFold-Multimer) in cross-kingdom interaction studies, reflecting interdisciplinary sophistication.

4. Competitive Funding Record

  • Secured prestigious funding from national (NSFC), provincial, and postdoctoral foundations in China as Principal Investigator, demonstrating independent scientific leadership.

5. International Collaboration & Mobility

  • Experience at institutions in China, the UK, and the USA, showcasing global integration and collaborative capacity.

  • Short-term training and collaborative publications with international partners, enhancing his scientific network and adaptability.

🎓 Education

 Dr. Huang began his academic journey with a Bachelor’s degree in Plant Science from Anhui Agricultural University (2009–2013). He then pursued his Ph.D. in Plant Pathology at Nanjing Agricultural University (2013–2018), where he was mentored by the esteemed Prof. Suomeng Dong. His doctoral research laid a strong foundation for his expertise in host–pathogen molecular dynamics.

🧪 Experience

 Following his Ph.D., Dr. Huang worked as a postdoctoral researcher at Nanjing Agricultural University (2018–2021), continuing under Prof. Dong’s supervision. In 2019, he broadened his global research exposure as a visiting scholar at Colorado State University with Prof. Anireddy Reddy. Since January 2022, he has been advancing his research at the University of Oxford under Prof. Renier A. L. van der Hoorn, contributing to frontier studies in plant proteomics and immunity.

🔬 Research Interests On Biological Sciences

🌿 Dr. Huang’s research delves into:

  • Alternative splicing in plant immunity

  • Effector biology in oomycete pathogens

  • Protease-targeting mechanisms at the plant–pathogen interface

  • Use of AlphaFold and other computational tools to predict protein interactions
    His work bridges molecular biology, bioinformatics, and biotechnology for improving crop resistance strategies.

🏆 Awards and Funding

 As a Principal Investigator, Dr. Huang has secured several prestigious research grants, including:

  • National Natural Science Foundation of China (No. 31901862)

  • Natural Science Foundation of Jiangsu Province (SBK2019040604)

  • Fundamental Research Funds for Central Universities (KYQN202009)

  • China Postdoctoral Science Foundation (2018M640494)

  • Special Postdoctoral Science Fund (2020T130306)

These awards reflect his scientific rigor and innovative research in plant molecular biology.

📚 Publications

1. A Phytophthora effector manipulates host histone acetylation and reprograms defense gene expression to promote infection
Authors: L Kong, X Qiu, J Kang, Y Wang, H Chen, J Huang, M Qiu, Y Zhao, G Kong, …
Year: 2017
Cited by: 144

2. An oomycete plant pathogen reprograms host pre-mRNA splicing to subvert immunity
Authors: J Huang, L Gu, Y Zhang, T Yan, G Kong, L Kong, B Guo, M Qiu, Y Wang, …
Year: 2017
Cited by: 120

3. Phytophthora effectors modulate genome-wide alternative splicing of host mRNAs to reprogram plant immunity
Authors: J Huang, X Lu, H Wu, Y Xie, Q Peng, L Gu, J Wu, Y Wang, ASN Reddy, …
Year: 2020
Cited by: 84

4. The Activation of Phytophthora Effector Avr3b by Plant Cyclophilin is Required for the Nudix Hydrolase Activity of Avr3b
Authors: G Kong, Y Zhao, M Jing, J Huang, J Yang, Y Xia, L Kong, W Ye, Q Xiong, …
Year: 2015
Cited by: 84

5. The Phytophthora sojae RXLR effector Avh238 destabilizes soybean Type2 GmACSs to suppress ethylene biosynthesis and promote infection
Authors: B Yang, Y Wang, B Guo, M Jing, H Zhou, Y Li, H Wang, J Huang, Y Wang, …
Year: 2019
Cited by: 71

6. AlphaFold-Multimer predicts cross-kingdom interactions at the plant-pathogen interface
Authors: F Homma, J Huang, RAL van der Hoorn
Year: 2023
Cited by: 69

7. Pathogen manipulation of chloroplast function triggers a light-dependent immune recognition
Authors: C Gao, H Xu, J Huang, B Sun, F Zhang, Z Savage, C Duggan, T Yan, …
Year: 2020
Cited by: 65

8. Cleavage of a pathogen apoplastic protein by plant subtilases activates host immunity
Authors: S Wang, R Xing, Y Wang, H Shu, S Fu, J Huang, JK Paulus, M Schuster, …
Year: 2021
Cited by: 40

9. Natural allelic variations provide insights into host adaptation of Phytophthora avirulence effector PsAvr3c
Authors: J Huang, L Chen, X Lu, Q Peng, Y Zhang, J Yang, BY Zhang, B Yang, …
Year: 2019
Cited by: 32

10. Phytophthora sojae apoplastic effector AEP1 mediates sugar uptake by mutarotation of extracellular aldose and is recognized as a MAMP
Authors: Y Xu, Y Zhang, J Zhu, Y Sun, B Guo, F Liu, J Huang, H Wang, S Dong, …
Year: 2021
Cited by: 31

📝 Conclusion

🌟 Dr. Jie Huang is a rising star in plant molecular biology, combining classical genetics, proteomics, and cutting-edge computational tools to unravel the complexities of plant immunity and pathogen virulence. His international collaborations, funding success, and impactful publications position him as a strong nominee for any prestigious research award recognizing scientific excellence in plant sciences.

Qingbao Guo | Neuroscience | Outstanding Scientist Award

Prof. Qingbao Guo | Neuroscience | Outstanding Scientist Award

Xi’an No.9 Hospital | China

Prof. Qingbao Guo is a highly accomplished Associate Chief Physician in the Department of Neurosurgery at the Second Affiliated Hospital of the Air Force Medical University (formerly Tangdu Hospital), China. He specializes in cerebrovascular disorders, brain tumors, and functional neurosurgery, and is recognized for his excellence in the diagnosis and treatment of moyamoya disease and other complex neurological conditions.

Professional profile👤

ORCID

Scopus

Strengths for the Awards✨

  1. Extensive Clinical Experience:

    • Over 20 years of progressive clinical practice in neurosurgery, including leadership as Associate Chief Physician at a top-tier military hospital.

    • Strong surgical expertise in cerebrovascular diseases, brain tumors, and functional neurosurgery, which are critical areas in modern neurosurgical practice.

  2. Academic Qualifications & Research:

    • A recent Ph.D. in Neurosurgery (2021–2024) focused on moyamoya disease (MMD)—a rare but significant cerebrovascular disorder.

    • Earlier Master’s-level research on peripheral vascular diseases, showing continuity in vascular-focused research.

    • Mentorship under established experts (Professors Lian Duan and Yanzheng He), enhancing academic rigor.

  3. Contribution to National Defense Health System:

    • His long-term service in military medical institutions (Air Force Medical University) underscores contributions to military medicine, a high-impact field with national importance.

  4. Interdisciplinary Relevance:

    • His work bridges clinical practice and surgical innovation, especially in the surgical management of complex neurological diseases, offering translational value to both academic and applied medicine.

🎓 Education

Prof. Qingbao Guo began his academic journey with a Bachelor’s degree in Clinical Medicine from Yan’an University (1999–2004). He furthered his specialization with a Master’s degree in Surgery (2008–2011) from Southwest Medical University, under the supervision of Prof. Yanzheng He, where he focused on clinical approaches to peripheral vascular diseases. Most recently, he earned his Ph.D. in Neurosurgery (2021–2024) from the Chinese PLA Medical School, mentored by Prof. Lian Duan, with research concentrating on the pathogenesis and surgical management of moyamoya disease.

💼 Professional Experience

Prof. Qingbao Guo has an extensive and progressive professional background in neurosurgery. He is currently serving as an Associate Chief Physician at Tangdu Hospital since September 2012, where he has amassed advanced surgical experience in managing brain tumors, vascular pathologies, and functional neurosurgical disorders. Prior to this, he was an Attending Physician at the First Affiliated Hospital of Southwest Medical University (July 2011 – August 2012), where he handled numerous vascular cases. His medical career began as a Resident Physician at Shaanxi Sengong Hospital (July 2004 – August 2008).

🔬 Research Interests On Neuroscience

Prof. Qingbao Guo’s research focuses on the pathophysiology and surgical treatment of cerebrovascular diseases, particularly moyamoya disease, a rare but serious condition affecting intracranial arteries. He is also interested in neuro-oncology, vascular neurosurgery, and advancements in functional neurosurgical procedures, with a vision to bridge translational neuroscience and surgical innovation.

🏆 Awards & Nominations

Prof. Qingbao Guo has been acknowledged for his clinical excellence and academic contribution through multiple hospital-level and regional honors. He is a nominee for the [Insert Award Name Here, e.g., “Outstanding Neurosurgeon Researcher Award 2025”] in recognition of his pioneering work in moyamoya disease surgical treatment and his consistent commitment to patient-centered research and education.

📚 Publications

🔬 Genetic Associations and Polymorphisms
  1. MTHFR Polymorphism and EDAS-induced Collateral Formation

    • [DOI: 10.3171/2024.1.JNS232121]
      Highlights the genetic influence (MTHFR) on surgical angiogenesis success post-EDAS in MMD patients.

  2. RNF213 p.R4810K Variant and Unfavorable Outcomes in Pediatric EDAS

    • [DOI: 10.1155/2024/1844190]
      Strong linkage of the RNF213 mutation with poor long-term outcomes, particularly relevant in East Asian populations.

🧪 Biomarker and Multi-Omics Studies
  1. Proteomic & Metabolomic Profiles in Pediatric MMD

    • [DOI: 10.2147/JIR.S471538]
      Identifies core disrupted pathways, potentially pointing toward new diagnostic or therapeutic targets.

  2. Complement C3 Expression & Postoperative Vasculopathy

    • [DOI: 10.2147/JIR.S451538]
      Suggests inflammatory markers like C3 as predictors of vascular changes post-intervention.

🧠 Neuroimaging and Risk Stratification
  1. MRI Vessel Wall Enhancement and MMD Outcomes

    • [DOI: 10.1007/S00330-023-10535-0]
      High-resolution MRI features were linked to clinical risk, potentially informing preoperative planning.

  2. Nomograms for Predicting Rebleeding and Outcomes

    • [DOI: 10.3171/2024.2.JNS232744]
      Well-validated clinical tools that integrate genetics and clinical features for long-term prognosis.

🧬 Pathophysiology and Comorbid Disease Connections
  1. Transcriptomics in MMD and SLE Crosstalk

    • [DOI: 10.3389/FIMMU.2024.1456392]
      A novel systems biology approach to uncover common pathways between MMD and autoimmune diseases like SLE.

  2. ZEB2 and Brain Microvascular Dysfunction Post-ICH

    • [DOI: 10.1080/15384101.2021.1959702]
      Delves into molecular mechanisms of endothelial dysfunction, bridging stroke and hemorrhage pathology.

📉 Risk Factors in Pediatric and Elderly Cohorts
  1. Preoperative Infarction & Pediatric Risk Factors

    • [DOI: 10.1007/S12975-023-01167-Z]
      Targeted focus on predictive markers in vulnerable pediatric populations.

  2. Outcomes in Elderly Post-Conservative vs. EDAS Treatment

  • [DOI: 10.3171/2023.7.JNS231060]
    Offers insights into age-specific management strategies and long-term care plans.

🔚 Conclusion

Prof. Qingbao Guo stands out as a dedicated neurosurgeon, educator, and researcher, committed to transforming patient outcomes through clinical expertise and scientific inquiry. His extensive training, hands-on experience, and impactful research make him a compelling candidate for any award celebrating excellence in medical and surgical innovation.