Assoc. Prof. Dr. Zerrin Kutlu | Biochemistry, Genetics and Molecular Biology | Research Excellence Award
Ataturk University | Turkey
Assoc. Prof. Dr. Zerrin Kutlu is a leading biochemist whose research focuses on oxidative stress, endoplasmic reticulum (ER) stress, inflammation, and diabetes-related complications, with an emphasis on elucidating molecular mechanisms underlying organ injury and cardiometabolic disorders. Her work spans ischemic heart injury, sepsis-induced organ damage, osteoporosis, and metabolic disease models, highlighting the interplay between oxidative stress and cellular dysfunction. Dr. Zerrin Kutlu has authored 15 Scopus-indexed publications, cited 211 times, with an h-index of 9, reflecting the impact and recognition of her research in the scientific community. She has contributed book chapters and served extensively as a peer reviewer and editorial board member for high-impact journals. Her pioneering studies on avasopasem manganese as a superoxide dismutase mimetic, alongside investigations of ATE1 enzyme biology, have provided novel insights into therapeutic strategies for diabetes, cardiovascular disease, and neurodegenerative disorders. She has advanced translational research through nanotechnology-based drug delivery systems, phenolic compound-loaded nanoparticles, and bioactive natural molecules, demonstrating the therapeutic potential of antioxidant and cytoprotective agents. In collaboration with industry and interdisciplinary teams, Dr. Zerrin Kutlu has developed boron-based bioactive compounds for dermo cosmetic and UV-protective applications, supported by TÜBİTAK-funded projects. Her portfolio includes multiple patents, international publications, and leadership in multi-center experimental studies, underscoring her commitment to innovation and scientific excellence. Through these contributions, Dr. Zerrin Kutlu has significantly advanced understanding of redox biology, ER stress modulation, and translational pharmacology, establishing herself as a recognized leader in biomedical research and therapeutic innovation.
Profiles: Scopus | Google Scholar | ORCID | ResearchGate | LinkedIn
Featured Publications
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Dumlu, F. A., Aydin, T., Odabasoglu, F., Berktas, O. A., Kutlu, Z., Erol, H. S., … (2019). Anti-inflammatory and antioxidant properties of jervine, a steroidal alkaloid from rhizomes of Veratrum album. Phytomedicine, 55, 191–199.
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Koc, K., Geyikoglu, F., Cakmak, O., Koca, A., Kutlu, Z., Aysin, F., Yilmaz, A., … (2021). The targets of β-sitosterol as a novel therapeutic against cardio-renal complications in acute renal ischemia/reperfusion damage. Naunyn-Schmiedeberg’s Archives of Pharmacology, 394(3), 469–479.
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Karaoğlan, E. S., Albayrak, A., Kutlu, Z., & Bayır, Y. (2018). Gastroprotective and antioxidant effects of Eremurus spectabilis Bieb. methanol extract and its isolated component isoorientin on indomethacin-induced gastric damage. Acta Cirúrgica Brasileira, 33, 609–618.
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Akpinar, E., Kutlu, Z., Kose, D., Aydin, P., Tavaci, T., Bayraktutan, Z., & Yuksel, T. N. (2022). Protective effects of idebenone against sepsis-induced acute lung damage. Journal of Investigative Surgery, 35(3), 560–568.
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Kutlu, Z., Celik, M., Bilen, A., Halıcı, Z., Yıldırım, S., Karabulut, S., & Karakaya, S. (2020). Effects of umbelliferone isolated from the Ferulago pauciradiata Boiss. & Heldr. plant on cecal ligation and puncture-induced sepsis model in rats. Biomedicine & Pharmacotherapy, 127, 110206.
