Alphonse Houssou Hounye | medicine | Best Researcher Award

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Dr. Alphonse Houssou Hounye | Medicine | Best Researcher Award

Second Xiangya Hospital | Central south university | China

Dr. Hounye Alphonse Houssou is a dedicated mathematician and researcher currently affiliated with the General Surgery Department at the Second Xiangya Hospital, Central South University, China. With a focus on bioinformatics, image processing, and statistical machine learning, Dr. Houssou is recognized for his significant contributions to scientific research, particularly in cancer prognosis and machine learning models.

Profile

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Strengths for the Awards

Dr. Alphonse Hounye Houssou demonstrates exceptional strengths in the field of scientific research, particularly in bioinformatics, image processing, and machine learning. His contributions include:

  1. Extensive Research Output: With 32 research papers and 21 SCI-indexed publications, including eight as the first author, Dr. Houssou has proven his ability to publish high-quality and impactful research.
  2. Innovative Contributions: His work on high-dimensional omics data analysis has led to groundbreaking findings, such as identifying hub immune-related genes (TRIM67, CORT, PSPN, SCAMP5, RFXAP) in pancreatic cancer prognosis.
  3. Recognition and Awards: He has earned multiple prestigious awards, including the ITCIE Award, Best Researcher Award (International Research Awards), and the Outstanding International Student Award (2022–2023).
  4. Leadership and Collaboration: Dr. Houssou has collaborated with over 10 institutions, participated in COVID-19-related research projects, and contributed to academic seminars, showcasing his leadership and teamwork abilities.

Education 🎓

Dr. Hounye Alphonse Houssou obtained a B.S. in Mathematics from Abomey-Calavi University, Benin, and earned an M.S. in Mathematical Statistics from JiangXi University of Finance and Economics, China, in 2015 and 2020, respectively. Currently, he is pursuing a Ph.D. at the School of Mathematics and Statistics, Central South University, China.

Experience 🏢

With extensive academic and professional experience, Dr. Houssou has been part of numerous innovative research projects. He has also contributed to COVID-19-related academic seminars and exhibited leadership across multidisciplinary teams. Additionally, he actively collaborates with over 10 research institutions globally, contributing to groundbreaking scientific advancements.

Research Interests On medicine🔬

Dr. Houssou’s research interests include:

  • Bioinformatics
  • Image Processing
  • Statistical and Deep Machine Learning

His work focuses on analyzing high-dimensional omics data, developing individualized risk assessments, and uncovering disease biomarkers for improved diagnostics and treatments, particularly in oncology.

Awards 🏆

Dr. Houssou has received several prestigious accolades:

  • ITCIE Award for research excellence
  • Best Researcher Award (International Research Award on Advanced Nanomaterials and Nanotechnology)
  • Outstanding International Student Award (2022–2023)

These awards reflect his contributions to advanced scientific research and innovation.

Publications 📚

  • Title: Characterization of PANoptosis-related genes in Crohn’s disease by integrated bioinformatics, machine learning, and experiments
    Authors: Yang, Y., Hounye, A.H., Chen, Y., Shi, G., Xiao, Y.
    Year: 2024
    Citations: 2
  • Title: A graph-optimized deep learning framework for recognition of Barrett’s esophagus and reflux esophagitis
    Authors: Hou, M., Wang, J., Liu, T., Wang, K., Chen, S.
    Year: 2024
    Citations: 0
  • Title: Explainable machine learning model identified potential biomarkers in liver cancer survival prediction
    Authors: Pan, Q., Houssou Hounye, A., Miao, K., Hou, M., Xiong, L.
    Year: 2024
    Citations: 0
  • Title: Automated heart disease prediction using improved explainable learning-based technique
    Authors: Bizimana, P.C., Zhang, Z., Hounye, A.H., Hammad, M., El-Latif, A.A.A.
    Year: 2024
    Citations: 3
  • Title: Explainable cancer factors discovery: Shapley additive explanation for machine learning models demonstrates the best practices in the case of pancreatic cancer
    Authors: Su, L., Hounye, A.H., Pan, Q., Hou, M., Xiong, L.
    Year: 2024
    Citations: 1
  • Title: Exploring explainable machine learning and Shapley additive explanations (SHAP) technique to uncover key factors of HNSC cancer: An analysis of the best practices
    Authors: Miao, K., Houssou Hounye, A., Su, L., Hou, M., Xiong, L.
    Year: 2024
    Citations: 5
  • Title: Integrated explainable machine learning and multi-omics analysis for survival prediction in cancer with immunotherapy response
    Authors: Hounye, A.H., Xiong, L., Hou, M.
    Year: 2024
    Citations: 0
  • Title: SCARNet: using convolution neural network to predict time series with time-varying variance
    Authors: Zhao, S., Kong, M., Li, R., Hou, M., Cao, C.
    Year: 2024
    Citations: 1
  • Title: Modeling SARS coronavirus-2 omicron variant dynamic via novel fractional derivatives with immunization and memory trace effects
    Authors: Liu, T., Yin, X., Liu, Q., Houssou Hounye, A.
    Year: 2024
    Citations: 1
  • Title: Evaluation of drug sensitivity, immunological characteristics, and prognosis in melanoma patients using an endoplasmic reticulum stress-associated signature based on bioinformatics and pan-cancer analysis
    Authors: Hounye, A.H., Hu, B., Wang, Z., Hou, M., Qi, M.
    Year: 2023
    Citations: 0

Conclusion ✅

Dr. Hounye Alphonse Houssou is a dynamic researcher dedicated to advancing machine learning applications in bioinformatics and medical diagnostics. His impactful contributions to cancer prognosis, along with numerous publications and awards, underscore his role as a leading scientist in the field.

Tadeusz Dobosz | Molecular Medicine | Best Researcher Award

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Prof. Tadeusz Dobosz | Molecular Medicine | Best Researcher Award

Retired | University of Medicine Wroclaw | Poland

Tadeusz Dobosz, is a distinguished medical scientist and forensic geneticist. Married with two children, he has made significant contributions to the fields of molecular biology, medical genetics, and forensic science. A retired professor, Dobosz is known for his expertise in DNA technologies, paternity testing, and seroanthropology. He has authored over 75 publications on the Philadelphia List, 515 additional papers, and oral presentations with a Hirsch Index of 20. Currently, he is focused on developing a Museum of Medicine.

Profile

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Strenghts for the Awards

  1. Extensive Academic and Professional Experience:
    • Over 49 years of professional engagement in biochemistry, molecular biology, forensic genetics, and medical genetics.
    • Progression from Assistant to University Professor and Head of the Molecular Techniques Unit at the Medical University of Wrocław.
    • Leadership roles in establishing and managing research laboratories, including Molecular Medicine, Paternity Testing, Forensic Genetics, and Seroanthropology.
  2. Research Contributions:
    • Authored 75 publications indexed in the Philadelphia List and over 515 additional papers, oral presentations, and posters.
    • Hirsch Index of 20, indicating a significant impact on the scientific community.
    • Expertise in cutting-edge forensic and genetic technologies, including PCR, SNP analysis, and DNA sequencing.
  3. Pioneering Work in Forensic Science and Genetics:
    • Specializes in human remains identification, ancient DNA (aDNA) research, and non-destructive DNA extraction methods.
    • Innovations in seroanthropology and forensic ballistics, including DNA deposits on weapons, cases, and bullets.
    • Contributions to paternity testing and biological trace investigations.
  4. Legacy and Knowledge Sharing:
    • Continuation of professional contributions post-retirement by organizing a Museum of Medicine and Hospital Museum.
    • A mentor and guide to the next generation of researchers in the Molecular Techniques Unit.
  5. Interdisciplinary Research Interests:
    • Combines molecular genetics with medical diagnostics, forensic ballistics, and even museology, showcasing a holistic and diverse approach to science.

Education 🎓

  • 1963: Graduated from Primary School.
  • 1967: Completed High School.
  • 1971: Earned a degree in Biochemistry from the University of Wrocław.
  • 1977: Achieved a Ph.D. in Immunology.
  • 2001: Obtained Habilitation in Medical Genetics.
  • 2007: Awarded the title of University Professor in Medical Science.

Experience 💼

Tadeusz Dobosz’s career spans diverse roles in biochemistry, immunology, and forensic science:

  • 1971-1974: Ph.D. student and Assistant at the Polish Academy of Sciences.
  • 1975: Expert in the Police Laboratory of Criminalistics.
  • 1979: Lecturer at the Medical University, Department of Forensic Medicine, Wrocław.
  • 2002: Senior Lecturer at the Medical University of Wrocław.
  • 2004-2020: Head of the Molecular Techniques Unit, leading four specialized laboratories in Molecular Medicine, Paternity Testing, Forensic Genetics, and Seroanthropology.
  • 2020: Retired and now actively organizes the Museum of Medicine.

Research Interests 🔬

Professor Dobosz specializes in:

  • Forensic genetics and human remains identification.
  • Ancient DNA (aDNA) preparation, repair, and testing.
  • Non-destructive DNA isolation methods from valuable specimens.
  • DNA computing and forensic ballistics (e.g., DNA traces on weapons and bullets).
    Additionally, he has a keen interest in medical diagnostics using PCR and museology in medicine.

Awards and Recognition 🏆

Although specific awards are not listed, Professor Dobosz’s prolific contributions to molecular genetics and forensic science have established him as a leader in his field. His Hirsch Index of 20 underscores the impact of his work in the scientific community.

Publications 📚

  • “PPARs in Clinical Experimental Medicine after 35 Years of Worldwide Scientific Investigations and Medical Experiments”
    • Authors: Skoczyńska, A.; Ołdakowska, M.; Dobosz, A.; Małodobra-Mazur, M.; Dobosz, T.
    • Year: 2024
    • Citations: 1
  • “DNA Content of Various Fluids and Tissues of the Human Body”
    • Authors: Siuta, J.; Dobosz, A.; Kawecki, J.; Dobosz, T.
    • Year: 2024
    • Citations: 2
  • “The hero of American and Polish nations: a molecular look at Thaddeus Kosciuszko’s cause of death suggests a contribution of endocarditis caused by Cutibacterium acnes infection”
    • Authors: Witt, M.; Tokarski, M.; Ziętkiewicz, E.; Jurek, T.; Dobosz, T.
    • Year: 2022
    • Citations: 0
  • “Analysis of polymorphism in 11 STR markers in the European red deer (Cervus elaphus) population in Poland”
    • Authors: Jonkisz, A.; Lebioda, A.; Cierzniak, A.; Dobosz, T.; Małodobra-Mazur, M.
    • Year: 2022
    • Citations: 0
  • “Inheritance vs. infectivity as a mechanism of malady and death of Frederic Chopin”
    • Authors: Witt, M.; Dobosz, T.
    • Year: 2021
    • Citations: 3
  • “Histone modifications influence the insulin-signaling genes and are related to insulin resistance in human adipocytes”
    • Authors: Małodobra-Mazur, M.; Cierzniak, A.; Myszczyszyn, A.; Kaliszewski, K.; Dobosz, T.
    • Year: 2021
    • Citations: 12
  • “PpMolecular Medicinearg hypermethylation as the first epigenetic modification in newly onset insulin resistance in human adipocytes”
    • Authors: Małodobra-Mazur, M.; Cierzniak, A.; Kaliszewski, K.; Dobosz, T.
    • Year: 2021
    • Citations: 15
  • “DNA methylation in adipocytes from visceral and subcutaneous adipose tissue influences insulin-signaling gene expression in obese individuals”
    • Authors: Cierzniak, A.; Pawelka, D.; Kaliszewski, K.; Dobosz, T.; Małodobra-Mazur, M.
    • Year: 2021
    • Citations: 12
  • “Original and generic clopidogrel: A comparison of antiplatelet effects and active metabolite concentrations in patients without polymorphisms in the ABCB1 gene and the allele variants CYPC192 and 3″
    • Authors: Wójcik, T.; Szymkiewicz, P.; Ściborski, K.; Jonkisz, A.; Protasiewicz, M.
    • Year: 2021
    • Citations: 2
  • “Metabolic differences between subcutaneous and visceral adipocytes differentiated with an excess of saturated and monounsaturated fatty acids”
    • Authors: Małodobra-Mazur, M.; Cierzniak, A.; Pawełka, D.; Rudnicki, J.; Dobosz, T.
    • Year: 2020
    • Citations: 27

Conclusion ✨

Tadeusz Dobosz has left an indelible mark on forensic science, molecular biology, and medical genetics. From pioneering DNA sequencing techniques to advancing paternity testing and forensic genetics, his work has significantly impacted these fields. Even in retirement, his passion for medicine and science continues through his dedication to museology, ensuring that future generations benefit from his expertise and vision.