Zhengfeng Jia | Medicine | Excellence in Research

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Prof. Dr. Zhengfeng Jia | Medicine | Excellence in Research

Fourth medical PLA general hospital | China

Dr. Zhengfeng Jia is a researcher in orthopedic biomechanics, focusing on distal humerus fractures, musculoskeletal dynamics, and finite element analysis. Affiliated with the Chinese PLA General Hospital and the National Clinical Research Center for Orthopedics, his work bridges computational modeling and clinical applications to optimize fracture fixation and rehabilitation strategies.

Professional profile👤

Scopus

Strengths for the Awards✨

  1. Innovative Methodology

    • The study integrates musculoskeletal dynamics (AnyBody software) with finite element analysis (Abaqus) to simulate real-world biomechanical conditions, overcoming the limitations of traditional static models.

    • The AnyBody-Abaqus coupling technique provides dynamic loading conditions, capturing muscle forces and joint reactions during elbow flexion/extension, which is rare in orthopedic biomechanics research.

  2. Clinical Relevance

    • Addresses a critical gap in distal humerus fracture management by quantifying “safe activity windows” for postoperative rehabilitation (e.g., ≤80° flexion for parallel plates, ≤30° for vertical plates).

    • Findings directly inform surgical decisions (e.g., plate configuration) and rehabilitation protocols to reduce complications like non-union.

  3. Rigorous Validation

    • Validates muscle forces using electromyography (EMG) literature and mesh convergence studies to ensure computational accuracy (<5% error).

    • Anatomical accuracy is confirmed via statistical shape modeling (SSM) and iterative closest point (ICP) algorithms (<1.2 mm error).

  4. High-Impact Results

    • Demonstrates that parallel plates outperform vertical plates in maintaining interfragmentary motion (IFM) within the healing threshold (0.06–0.20 mm).

    • Identifies stress migration paths in the humerus, correlating with anatomical weak zones (e.g., lateral condyle).

  5. Interdisciplinary Approach

    • Combines orthopedic surgery, biomechanics, and computational modeling, aligning with the trend of “smart orthopedics.”

Education 🎓

  • PhD Candidate in Orthopedics, Graduate School of Medical School of Chinese PLA Hospital, Beijing (Current).

  • Research training in musculoskeletal dynamics, 3D modeling, and finite element analysis (FEA).

Experience 💼

  • Researcher at the Fourth Medical Center of Chinese PLA General Hospital, Beijing.

  • Specializes in digital orthopedic technologies, including AnyBody-Abaqus joint modeling and biomechanical simulations.

  • Collaborates on studies quantifying “safe activity windows” for postoperative rehabilitation.

Research Interests On Medicine 🔍

  • Biomechanics of distal humerus fractures.

  • Musculoskeletal dynamics and finite element analysis (FEA).

  • Optimization of internal fixation plates and rehabilitation protocols.

  • AI applications in orthopedic decision-making.

Awards & Nominations 🏆

  • National Clinical Research Center for Orthopedics Grant (2024) for data-driven ulnar prostheses research.

  • Ethical approval recipient (2024KY005-KS001) for studies on fracture healing biomechanics.

Publications 📚

  1. Jia, Z., Xu, C., Gao, W., et al. (2025). Evaluation of internal fixation stability of distal humerus C-type fractures based on musculoskeletal dynamics: Finite element analysis under dynamic loading. Journal of Orthopaedic Surgery and Research, *20*(475).

  2. Contributed to meta-analyses on continuous passive motion post-arthroplasty (J Orthop Surg Res, 2024).

Conclusion 🌟

Zhengfeng Jia’s multidisciplinary research quantifies biomechanical thresholds for fracture healing, emphasizing parallel plate configurations and 30–80° flexion safety windows. His integration of AnyBody-Abaqus modeling advances personalized rehabilitation strategies, with future aims to validate findings in clinical trials and AI-driven orthopedic solutions.

Haotai Xie | Medicine | Best Researcher Award

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Dr. Haotai Xie | Medicine | Best Researcher Award

Peking University First Hospital | China

Dr. Haotai Xie is a dedicated clinician and researcher at Peking University First Hospital, specializing in cardiovascular diseases and bioinformatics. With a passion for advancing precision cardiology, Dr. Xie integrates computational approaches into clinical practice, enhancing diagnostic accuracy and therapeutic strategies. His work spans biomarker discovery, algorithm development, and non-invasive myocardial ischemia evaluation. Dr. Xie has authored seven first-author SCI papers in high-impact journals, contributing significantly to cardiovascular medicine and epigenetics.

Professional profile👤

ORCID

Scopus

Strengths for the Awards✨

  • Academic Productivity: Published seven first-author SCI papers in prestigious journals like Nucleic Acids Research, Briefings in Bioinformatics, and JAHA, accumulating a total impact factor exceeding 40.
  • Innovative Research: Co-developed PhaSepDB and MloDisDB, which have become cornerstone resources in phase separation research, cited in over 50 studies.
  • Interdisciplinary Expertise: Bridges cardiovascular medicine and bioinformatics, applying computational methods to improve diagnostic tools and biomarker discovery, enhancing precision cardiology.
  • Significant Contributions: Pioneered the characterization of cardiovascular phenotypes in Kleefstra syndrome, leading to evidence-based screening protocols, with direct implications for clinical guidelines and rare disease management.
  • Research Impact: Work has advanced the understanding of cardiovascular epigenetics and contributed to earlier diagnosis and more personalized treatment strategies.

🎓 Education

  • Doctorate in Clinical Medicine, Peking University First Hospital, China.

💼 Experience

  • Doctor, Peking University First Hospital.
  • Lead researcher in interdisciplinary projects bridging computational biology and cardiovascular medicine.
  • Co-developed PhaSepDB and MloDisDB, pivotal resources for phase separation research.

🔬 Research Interests On Medicine

  • Cardiovascular Medicine
  • Bioinformatics
  • Precision Cardiology
  • Biomarker Discovery
  • AI-driven Diagnostic Tools

🏆 Awards

  • Recognized for sustained academic productivity and innovation in cardiovascular research.

📓 Publications

  • “Association between urinary sodium excretion and all-cause mortality: a cohort study in a Chinese community-based population”

    • Year: 2025
    • Authors: Haotai Xie, Xinyan Wen, Fangfang Fan, Jia Jia, Yong Huo, Yanjun Gong, Yan Zhang
    • Citations: Not available yet (published recently)

  • “Highlighting cardiovascular manifestations of Kleefstra syndrome: literature review and clinical insights”

    • Year: 2025
    • Authors: Haotai Xie, Pengkang He, Qinhui Sheng, Wei Ma, Yanjun Gong, Yan Zhang, Lin Qiu
    • Citations: Not available yet (published recently)

  • “Rethinking the Functional SYNTAX Score Threshold”

    • Year: 2024
    • Authors: Haotai Xie
    • Citations: Not available yet (upcoming publication)

  • “Research Progress and Clinical Value of Subendocardial Viability Ratio”

    • Year: 2024
    • Authors: Haotai Xie, Lan Gao, Fangfang Fan, Yanjun Gong, Yan Zhang
    • Citations: Not available yet (recent publication)

  • “PhaSepDB in 2022: annotating phase separation-related proteins with droplet states, co-phase separation partners and other experimental information”

    • Year: 2023
    • Authors: Chao Hou, Xinxin Wang, Haotai Xie, Taoyu Chen, Peiyu Zhu, Xiaofeng Xu, Kaiqiang You, Tingting Li
    • Citations: Not specified

  • “Application of B-Type Natriuretic Peptide in Neonatal Diseases”

    • Year: 2021
    • Authors: Haotai Xie, Yixuan Huo, Qinzheng Chen, Xinlin Hou
    • Citations: Not specified

  • “MloDisDB: a manually curated database of the relations between membraneless organelles and diseases”

    • Year: 2021
    • Authors: Chao Hou, Haotai Xie, Yang Fu, Yao Ma, Tingting Li
    • Citations: Not specified

🔔 Conclusion

Dr. Haotai Xie exemplifies the fusion of clinical expertise and computational innovation, driving advancements in cardiovascular medicine. His research has not only deepened the understanding of cardiovascular diseases but also paved the way for precision cardiology. With a robust publication record and interdisciplinary approach, Dr. Xie continues to shape the future of cardiovascular health management through groundbreaking discoveries and technological integration.