Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Prof. Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Tehran Medical Sciences, Islamic Azad University | Iran

Professor Mehrdad Hashemi is a renowned scholar in Molecular and Medical Genetics whose pioneering research has made transformative contributions to predictive, preventive, and personalized medicine. His scientific work focuses on the discovery of diagnostic and therapeutic biomarkers particularly non-coding RNAs (lncRNAs and miRNAs) with profound implications for early disease detection, molecular targeting, and precision therapy. Prof. Mehrdad Hashemi has authored 372 peer-reviewed publications indexed in Scopus, accumulating over 6,826 citations from 6,242 documents, and achieving a remarkable h-index of 41. His research portfolio includes 299 ISI-indexed papers, 342 Scopus-indexed papers, and 258 PubMed articles, encompassing 119 Q1 and 82 Q2 journals. He has led or completed 14 major research projects, contributed to 95 industrial and academic collaborations, and maintained 110 international research partnerships with leading institutions across the USA, UK, Canada, China, Germany, Australia, and beyond. His scholarly output also includes 3 internationally published books and 1 patent. Ranked among the World’s Top 1% and 2% Scientists in both ESI (2024) and Stanford (2024–2025) global rankings, Prof. Mehrdad Hashemi’s groundbreaking studies on exosomes, nanomedicine, gene regulation, and cancer therapeutics have advanced global understanding of disease mechanisms and innovative treatment modalities. He also contributes extensively as an editorial board member, peer reviewer, and thought leader in the field of molecular diagnostics and translational genetics.

Profiles: Scopus | Google Scholar | ORCID | Staff Page

Featured Publications

  • Paskeh, M. D. A., Entezari, M., Mirzaei, S., Zabolian, A., Saleki, H., Naghdi, M. J., … & Hashemi, M. (2022). Emerging role of exosomes in cancer progression and tumor microenvironment remodeling. Journal of Hematology & Oncology, 15(1), 83. https://doi.org/10.1186/s13045-022-01296-0

  • Bolhassani, A., Javanzad, S., Saleh, T., Hashemi, M., Aghasadeghi, M. R., … & Sadat, S. M. (2014). Polymeric nanoparticles: potent vectors for vaccine delivery targeting cancer and infectious diseases. Human Vaccines & Immunotherapeutics, 10(2), 321–332. https://doi.org/10.4161/hv.26796

  • Entezari, M., Hashemi, D., Taheriazam, A., Zabolian, A., Mohammadi, S., … & Hashemi, M. (2022). AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation. Biomedicine & Pharmacotherapy, 146, 112563. https://doi.org/10.1016/j.biopha.2021.112563

  • Hashemi, M., Moosavi, M. S., Abed, H. M., Dehghani, M., Aalipour, M., Heydari, E. A., … & Mirzaei, S. (2022). Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy. Pharmacological Research, 184, 106418. https://doi.org/10.1016/j.phrs.2022.106418

  • Sadrkhanloo, M., Entezari, M., Orouei, S., Ghollasi, M., Rezaei, S., Hejazi, E. S., … & Hashemi, M. (2022). STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response. Pharmacological Research, 182, 106311. https://doi.org/10.1016/j.phrs.2022.106311

Pingyu Zhang | Biochemistry | Best Researcher Award

Prof. Pingyu Zhang | Biochemistry | Best Researcher Award

Shenzhen University | China

Pingyu Zhang is a distinguished professor and deputy director of the Department of Chemistry at Shenzhen University. She obtained her Ph.D. in 2015 under the mentorship of Professor Hui Chao at Sun Yat-sen University. Following her doctoral studies, she joined the University of Warwick as a Newton Fellow in Professor Peter J. Sadler’s group from 2015 to 2017. Since 2017, she has been a faculty member at Shenzhen University, where she has made significant contributions to the field of chemistry. In recognition of her outstanding research, she was honored as a Young Chang Jiang Scholar by the Ministry of Education in 2023.

Professional profile👤

ORCID

Google Scholar

Scopus

Strengths for the Awards✨

  1. Outstanding Research Contributions

    • Professor Zhang has made significant advancements in the field of metal complex drugs for tumor-driven therapy, particularly in light- and sound-sensitive anti-tumor treatments.
    • Her pioneering work in sonodynamic therapy using metal complexes has opened new avenues for deep-tumor treatment, demonstrating high scientific impact.
  2. Academic Excellence & Recognitions

    • Recognized as a Young Chang Jiang Scholar (2023) by the Ministry of Education, a prestigious honor highlighting her research excellence.
    • Recipient of the Second-Class Natural Science Award of Shenzhen (2023, first contributor) and the Dalton Division Horizon Prize (2022) from the Royal Society of Chemistry.
  3. Research Productivity & Innovation

    • Published over 80 research papers in reputable journals, reflecting her consistent contributions to the scientific community.
    • Holds 18 Chinese invention patents, indicating her strong emphasis on translational research and innovation.
  4. International Experience & Collaborations

    • Gained global exposure through her postdoctoral research as a Newton Fellow at the University of Warwick (2015-2017) under the mentorship of Professor Peter J. Sadler.
    • Established a strong research presence both nationally and internationally, positioning her as a leading scientist in her field.

Education 🎓

Pingyu Zhang completed her Ph.D. in Chemistry at Sun Yat-sen University in 2015 under the guidance of Professor Hui Chao. Her academic journey equipped her with a strong foundation in metal complex chemistry, which later became a cornerstone of her research career.

Experience 💼

Following her Ph.D., Professor Zhang worked as a Newton Fellow at the University of Warwick from 2015 to 2017, collaborating with Professor Peter J. Sadler on groundbreaking research in metal-based therapeutics. In 2017, she joined Shenzhen University as a faculty member, where she currently serves as a distinguished professor and deputy director of the Department of Chemistry. Her leadership and dedication have significantly advanced the department’s research initiatives.

Research Interests On Biochemistry 🌍

Professor Zhang’s research focuses on the fundamental study of metal complex drugs for tumor-driven therapy. She has pioneered the development of light- and sound-sensitive anti-tumor drugs, creating innovative therapeutic strategies. Notably, she was the first to identify the potential application of metal complexes in sonodynamic therapy, a promising approach for treating deep-seated tumors. Her work aims to enhance cancer treatment efficacy while minimizing side effects.

Awards 🏆

  • Young Chang Jiang Scholar, Ministry of Education (2023)
  • Second-Class Natural Science Award of Shenzhen (First Contributor, 2023)
  • Dalton Division Horizon Prize, Royal Society of Chemistry (2022)

Publications 📚

Professor Zhang has published over 80 research papers in prestigious journals and holds 18 Chinese invention patents. Below are some of her notable publications:

  1. Highly stable single Pt atomic sites anchored on aniline-stacked graphene for hydrogen evolution reaction

    • Authors: S Ye, F Luo, Q Zhang, P Zhang, T Xu, Q Wang, D He, L Guo, Y Zhang, …
    • Year: 2019
    • Citations: 474
  2. Highly charged ruthenium (II) polypyridyl complexes as lysosome‐localized photosensitizers for two‐photon photodynamic therapy

    • Authors: H Huang, B Yu, P Zhang, J Huang, Y Chen, G Gasser, L Ji, H Chao
    • Year: 2015
    • Citations: 445
  3. Targeted photoredox catalysis in cancer cells

    • Authors: H Huang, S Banerjee, K Qiu, P Zhang, O Blacque, T Malcomson, …
    • Year: 2019
    • Citations: 398
  4. Advances in the design of organometallic anticancer complexes

    • Authors: P Zhang, PJ Sadler
    • Year: 2017
    • Citations: 392
  5. New designs for phototherapeutic transition metal complexes

    • Authors: C Imberti, P Zhang, H Huang, PJ Sadler
    • Year: 2020
    • Citations: 377
  6. Ruthenium (II) polypyridyl complexes as mitochondria-targeted two-photon photodynamic anticancer agents

    • Authors: J Liu, Y Chen, G Li, P Zhang, C Jin, L Zeng, L Ji, H Chao
    • Year: 2015
    • Citations: 278
  7. Targeting nucleus DNA with a cyclometalated dipyridophenazineruthenium (II) complex

    • Authors: H Huang, P Zhang, B Yu, Y Chen, J Wang, L Ji, H Chao
    • Year: 2014
    • Citations: 230
  8. Redox‐active metal complexes for anticancer therapy

    • Authors: P Zhang, PJ Sadler
    • Year: 2017
    • Citations: 213
  9. Boosting the alkaline hydrogen evolution of Ru nanoclusters anchored on B/N–doped graphene by accelerating water dissociation

    • Authors: S Ye, F Luo, T Xu, P Zhang, H Shi, S Qin, J Wu, C He, X Ouyang, Q Zhang, …
    • Year: 2020
    • Citations: 174
  10. Noncovalent ruthenium (II) complexes–single-walled carbon nanotube composites for bimodal photothermal and photodynamic therapy with near-infrared irradiation

  • Authors: P Zhang, H Huang, J Huang, H Chen, J Wang, K Qiu, D Zhao, L Ji, …
  • Year: 2015
  • Citations: 167

Conclusion 🎯

Pingyu Zhang is a leading researcher in the field of metal-based tumor therapy, with significant contributions to the development of innovative anti-cancer strategies. Through her pioneering work in sonodynamic and photodynamic therapy, she continues to push the boundaries of cancer treatment. Her numerous accolades, high-impact publications, and patents underscore her influence in the scientific community, making her a key figure in advancing metal complex drug research.