Prof. Yuyan Tang | Immunology and Microbiology | Best Researcher Award

Minhang Hospital, Fudan University | China

Prof. Yuyan Tang is a clinician-scientist specializing in nephrology and molecular immunopathology, with a strong research focus on the gut–kidney axis, IgA nephropathy, and chronic kidney disease (CKD). Her studies elucidate the mechanisms by which intestinal microbiota, short-chain fatty acids (SCFAs), and NLRP3 inflammasome signaling influence renal inflammation and fibrosis, integrating molecular biology with traditional Chinese medicine interventions. She has led several competitive research projects funded by the National Natural Science Foundation of China and regional scientific bodies, advancing translational insights into renal disease mechanisms and microbiome-based therapeutic strategies. Prof. Yuyan Tang has published 23 peer-reviewed documents indexed in Scopus, garnering 287 citations across 262 citing documents, with an h-index of 8. Her scientific contributions include 8 first- or corresponding-author SCI papers with a total impact factor of 52.7, notably featuring a highly cited article in Circulation Research and impactful publications in Nephrology Dialysis Transplantation and BMC Microbiology. Recognized as a Youth Talent Awardee at Fudan University’s Affiliated Minhang Hospital, Prof. Yuyan Tang’s research continues to bridge microbiome regulation and nephrology through innovative molecular and clinical investigations.

Profile: Scopus

Featured Publications

• Tang, Y., Zhu, Y., He, H., Sun, W., Wu, J., Xiao, Y., … Xu, X. (2024). IgA nephropathy: Gut microbiome regulates the production of hypoglycosylated IgA1 via the TLR4 signaling pathway. Nephrology Dialysis Transplantation, 39(10), 1624–1641.

• Jiang, L., He, H., Tang, Y., Li, J., Reilly, S., Xin, H., … Cai, H. (2024). Activation of BK channels prevents diabetes-induced osteopenia by regulating mitochondrial Ca2+ and SLC25A5/ANT2-PINK1-PRKN-mediated mitophagy. Autophagy, 20(11), 2388–2404.

• Li, H., Xu, M., Xu, X., Tang, Y., Jiang, H., Li, L., … Yang, T. (2022). Faecalibacterium prausnitzii attenuates CKD via Butyrate-Renal GPR43 Axis. Circulation Research, 131(9), e120–e134.

• Tang, Y., Xiao, Y., He, H., Zhu, Y., Sun, W., Hu, P., … Xu, X. (2023). Aberrant gut microbiome contributes to barrier dysfunction, inflammation and local immune responses in IgA nephropathy. Kidney and Blood Pressure Research, 48(1), 261–276.

• Tang, Y., Zhu, Y., He, H., Peng, Y., Hu, P., Wu, J., … Xu, X. (2022). Gut dysbiosis and intestinal barrier dysfunction promote IgA nephropathy by increasing the production of Gd-IgA1. Frontiers in Medicine, 9, 944027.