Carlos Alberto Pastore | Medicine and Health Sciences | Best Researcher Award

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Prof. Carlos Alberto Pastore | Medicine and Health Sciences | Best Researcher Award

Heart Institute of the Hospital das Clínicas of FMUSP | Brazil

Prof. Carlos Alberto Pastore is a distinguished cardiologist and researcher from the University of São Paulo, Brazil, internationally recognized for his pioneering work in electrocardiology and vectorcardiography. As a Professor and Medical Collaborator at the Faculty of Medicine, University of São Paulo (FMUSP), he has significantly advanced diagnostic methods for cardiac electrical diseases, cardiac mapping, and non-invasive electrocardiographic techniques. His research specializes in surface electrocardiographic mapping, high-resolution ECG, microalternans of the T wave (mTWA), and vectorcardiographic analysis of ventricular activation and repolarization abnormalities. Prof. Carlos Alberto Pastore has played a vital role in refining diagnostic criteria for arrhythmogenic disorders, ventricular hypertrophy, and cardiac resynchronization therapy, and he has applied artificial neural networks and machine learning in ECG-based cardiopathy detection in collaboration with the Federal University of Technology of Paraná (UTFPR). At InCor – Heart Institute (Hospital das Clínicas, FMUSP), he has held major roles including Director of the Clinical Unit of Resting Electrocardiography, Medical Director of Telemedicine, and Vice-President of the Zerbini Foundation, contributing to translational cardiology and digital health innovation. He also served as President (2013–2015) of the International Society of Electrocardiology (ISE) and is a Fellow of the European Society of Cardiology (FESC). According to Scopus (Author ID: 7006635654), Prof. Carlos Alberto Pastore has authored 53 scientific publications, received 1,014 citations from 948 documents, and holds an h-index of 12. His research has appeared in leading journals including the Journal of Electrocardiology, Annals of Noninvasive Electrocardiology, Arquivos Brasileiros de Cardiologia, and JACC, making him one of Brazil’s leading authorities in clinical electrocardiology and cardiovascular diagnostics.

Profiles: Scopus | Google Scholar | ORCID | ResearchGate

Featured Publications

• de Luna, A. B., Brugada, J., Baranchuk, A., Borggrefe, M., Breithardt, G., & Pastore, C. A. (2012). Current electrocardiographic criteria for diagnosis of Brugada pattern: A consensus report. Journal of Electrocardiology, 45(5), 433–442.* https://doi.org/10.1016/j.jelectrocard.2012.06.004

• de Luna, A. B., Platonov, P., Cosio, F. G., Cygankiewicz, I., Pastore, C., Baranowski, R., … & Spodick, D. (2012). Interatrial blocks: A separate entity from left atrial enlargement: A consensus report. Journal of Electrocardiology, 45(5), 445–451.* https://doi.org/10.1016/j.jelectrocard.2012.06.008

• Pastore, C. A., Pinho, J. A., Pinho, C., Samesima, N., Pereira Filho, H. G., & Mansur, A. P., et al. (2016). III Diretrizes da Sociedade Brasileira de Cardiologia sobre análise e emissão de laudos eletrocardiográficos. Arquivos Brasileiros de Cardiologia, 106(4 Suppl 1), 1–23.* https://doi.org/10.5935/abc.20160054

• Santos, I. S., Goulart, A. C., Brandão, R. M., Santos, R. C. O., Bittencourt, M. S., Sitnik, D., … & Pastore, C. A. (2015). One-year mortality after an acute coronary event and its clinical predictors: The ERICO study. Arquivos Brasileiros de Cardiologia, 105(1), 53–64.* https://doi.org/10.5935/abc.20150049

• Digby, G. C., Kukla, P., Zhan, Z. Q., Pastore, C. A., Piotrowicz, R., Schapachnik, E., … & Baranchuk, A. (2015). The value of electrocardiographic abnormalities in the prognosis of pulmonary embolism: A consensus paper. Annals of Noninvasive Electrocardiology, 20(3), 207–223.* https://doi.org/10.1111/anec.12235

Xiaowen Mao | Medicine and Health Sciences | Best Researcher Award

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Assist. Prof. Dr. Xiaowen Mao | Medicine and Health Sciences | Best Researcher Award

University of Macau | Macau

Dr. Xiaowen Mao, M.D., Ph.D., is an Assistant Professor at the State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, where she leads translational research on cancer biology, immunotherapy, and tumor microenvironment modulation. She earned her Ph.D. in Biomedical Sciences from the University of Hong Kong and her B.Sc. in Clinical Medicine from Shanghai Jiao Tong University, China. Her research focuses on extracellular vesicles, immune homeostasis, metabolic reprogramming in tumors, and hepatocellular carcinoma metastasis, integrating molecular, cellular, and translational approaches. Dr. Xiaowen Mao has led several high-impact projects as principal investigator, funded by the Health and Medical Research Fund, National Natural Science Foundation Young Scientist Fund, and FDCT Innovation and Technology Promotion. Her significant contributions include the development of broadly potent neutralizing antibodies targeting Nidogen 1 to inhibit tumor growth, elucidation of extracellular vesicle-mediated metabolic reprogramming in tumors, and advances in dendritic cell vaccine strategies. She holds a U.S. patent on Nidogen 1 as a diagnostic and therapeutic target for hepatocellular carcinoma, serves as Guest Editor for Frontiers in Endocrinology, and is an ad-hoc reviewer for multiple high-impact journals. According to Scopus, she has 31 publications, 1,114 citations by 1,010 documents, and an h-index of 20. Dr. Xiaowen Mao’s work bridges fundamental research and clinical translation, delivering innovative therapies and advancing precision medicine in oncology, while demonstrating a profound impact on cancer biology, immunotherapy, and translational research.

Profile: Scopus

Featured Publications

  • Xue, T. M., Yeung, C. L. S., Mao, X. W., Tey, S. K., Lo, K. W., Tang, H. N., Yun, J. P., & Yam, J. W. P. (2025). Development of a broadly potent neutralizing antibody targeting Nidogen 1 effectively inhibits cancer growth and metastasis in preclinical tumor models. Journal of Translational Internal Medicine. https://doi.org/10.1515/jtim-2025-0008

  • Xia, L., Li, C. G., Zhao, J., Sun, Q. C., & Mao, X. W.* (2025). Rebalancing immune homeostasis in combating disease: The impact of medicine food homology plants and gut microbiome. Phytomedicine, 136, 156150. https://doi.org/10.1016/j.phymed.2025.156150

  • Chen, Z., Yam, J. W. P., & Mao, X. W.* (2024). The multifaceted roles of small extracellular vesicles in metabolic reprogramming in the tumor microenvironments. Proteomics, e2300021. https://doi.org/10.1002/pmic.202300021

  • Lee, K. W., Yam, J. W. P., & Mao, X. W.* (2023). Dendritic cell vaccines: A shift from conventional approach to new generations. Cells, 12(2147). https://doi.org/10.3390/cells12172147

  • Li, S., Delvecchio, M., Ramkumar, K., Mao, X. W., Sun, X. D., & Guo, S. Z. (2023). Editorial: Clinical and genetic determinants of diabetes and complications. Frontiers in Endocrinology.