Dr. Tiziana Casoli | Neuroscience | Best Researcher Award

Senior Researcher | IRCCS INRCA | Italy

Dr. Tiziana Casoli is a Senior Researcher at IRCCS INRCA, specializing in Applied Genetics. Since 1992, she has been actively engaged in research at the Center for Neurobiology of Aging in Ancona, Italy. Her work focuses on identifying and evaluating physiological and pathological biomarkers of the aging nervous system. She has contributed to over 100 indexed publications and participated in numerous research projects as both Principal Investigator and afferent researcher. Casoli is also a proud member of the Italian Society of Geriatrics and Gerontology (SIGG) and the European Platform of Women Scientists (EPWS).

Professional profile👤

ORCID

Scopus

Strengths for the Awards✨

• Extensive Research Experience: Over three decades of dedicated research in neurobiology, focusing on aging, Alzheimer’s, and Parkinson’s disease.
• Notable Contributions: Significant contributions to understanding synaptic plasticity, mitochondrial dysfunction, and the identification of biomarkers in neurodegenerative diseases.
• Publications and Citation Impact: 104 indexed papers and a citation index of 25, demonstrating influence in the field.
• Leadership in Research Projects: Involvement in several high-impact projects as Principal Investigator (PI) and team member.
• Professional Recognition: Active member of SIGG and EPWS, reflecting engagement in scholarly communities.

Education 🎓

• Specialization in Applied Genetics, University of Bologna, Italy.

Experience 💼

• Senior Researcher, IRCCS INRCA, Center for Neurobiology of Aging, Ancona, Italy (1992 – Present).
• Principal Investigator and collaborator in various public and private research projects.

Research Interests On Neuroscience🔬

• Neurobiology of Aging
• Alzheimer’s Disease
• Parkinson’s Disease
• Biomarkers
• Mitochondria

Awards 🏆

• Member of the Italian Society of Geriatrics and Gerontology (SIGG).
• Member of the European Platform of Women Scientists (EPWS).

Publications 📄

1. Title: Late-onset major depressive disorder: exploring the therapeutic potential of enhancing cerebral brain-derived neurotrophic factor expression through targeted microRNA delivery

   • Authors: Giovanni Lai, Marco Malavolta, Serena Marcozzi, Giorgia Bigossi, Maria Elisa Giuliani, Tiziana Casoli, Marta Balietti
   • Year: 2024

2. Title: Analysis of mitochondrial DNA allelic changes in Parkinson’s disease: a preliminary study

   • Authors: Tiziana Casoli, Rosamaria Lisa, Paolo Fabbietti, Fiorenzo Conti
   • Year: 2020

3. Title: Cerebrospinal fluid biomarkers and cognitive status in differential diagnosis of frontotemporal dementia and Alzheimer’s disease

   • Authors: Tiziana Casoli, Susy Paolini, Paolo Fabbietti, Patrizia Fattoretti, Lucia Paciaroni, Katia Fabi, Beatrice Gobbi, Roberta Galeazzi, Roberto Rossi, Fabrizia Lattanzio et al.
   • Year: 2019

4. Title: My Mind Project: the effects of cognitive training for elderly—the study protocol of a prospective randomized intervention study

   • Authors: Giuli, C.; Fattoretti, P.; Gagliardi, C.; Mocchegiani, E.; Venarucci, D.; Balietti, M.; Casoli, T.; Costarelli, L.; Giacconi, R.; Malavolta, M. et al.
   • Year: 2016

5. Title: The effect of astaxanthin on the aging rat brain: Gender-related differences in modulating inflammation

   • Authors: Balietti, M.; Giannubilo, S.R.; Giorgetti, B.; Solazzi, M.; Turi, A.; Casoli, T.; Ciavattini, A.; Fattoretti, P.
   • Year: 2016

6. Title: Role of diffuse low-level heteroplasmy of mitochondrial DNA in Alzheimer’s disease neurodegeneration

   • Authors: Casoli, T.; Spazzafumo, L.; Di Stefano, G.; Conti, F.
   • Year: 2015

7. Title: Effect of cognitive training on the expression of brain-derived neurotrophic factor in lymphocytes of mild cognitive impairment patients

   • Authors: Casoli, T.; Giuli, C.; Balietti, M.; Giorgetti, B.; Solazzi, M.; Fattoretti, P.
   • Year: 2014

8. Title: One-month strawberry-rich anthocyanin supplementation ameliorates cardiovascular risk, oxidative stress markers and platelet activation in humans

   • Authors: Alvarez-Suarez, J.M.; Giampieri, F.; Tulipani, S.; Casoli, T.; Di Stefano, G.; González-Paramás, A.M.; Santos-Buelga, C.; Busco, F.; Quiles, J.L.; Cordero, M.D. et al.
   • Year: 2014

9. Title: Early selective vulnerability of synapses and synaptic mitochondria in the hippocampal CA1 region of the Tg2576 mouse model of Alzheimer’s disease

   • Authors: Balietti, M.; Giorgetti, B.; Casoli, T.; Solazzi, M.; Tamagnini, F.; Burattini, C.; Aicardi, G.; Fattoretti, P.
   • Year: 2013

10. Title: Platelets in Alzheimer’s disease-associated cellular senescence and inflammation

• Authors: Casoli, T.; Balietti, M.; Giorgetti, B.; Solazzi, M.; Scarpino, O.; Fattoretti, P.
• Year: 2013

11. Title: Dynamin binding protein gene expression and memory performance in aged rats

• Authors: Casoli, T.; Di Stefano, G.; Fattoretti, P.; Giorgetti, B.; Balietti, M.; Lattanzio, F.; Aicardi, G.; Platano, D.
• Year: 2012

Conclusion 📊

Tiziana Casoli’s career is marked by a deep commitment to understanding the complexities of aging and neurodegenerative diseases. Her contributions to biomarker identification and mitochondrial research have significantly advanced knowledge in the field, while her involvement in numerous high-impact projects showcases her dedication to improving the lives of aging populations. As an active member of SIGG and EPWS, she continues to inspire and collaborate with scientists worldwide.