Long Chang | Medicine and Health Sciences | Best Researcher Award

Dr. Long Chang | Medicine and Health Sciences | Best Researcher Award

Peking Union Medical College Hospital | China

Dr. Long Chang is an accomplished physician and clinical researcher whose career demonstrates excellence in patient care and significant contributions to hematology. He currently serves as an Attending Physician at the Department of Hematology, Peking Union Medical College Hospital, Beijing, China, building upon his medical training at Peking Union Medical College, Tsinghua University. His research focuses on rare hematologic disorders, particularly myeloproliferative neoplasms and histiocytic diseases, with emphasis on improving diagnostic precision, expanding therapeutic strategies, and enhancing patient outcomes. According to Scopus (Author ID: 57225110413), Dr. Long Chang has authored 39 publications, which have collectively received 165 citations across 152 documents, reflecting the impact of his work, and holds an h-index of 6. He has published influential studies in leading journals including Leukemia, EClinicalMedicine, Oncologist, and Orphanet Journal of Rare Diseases. His work has advanced treatment options for Rosai-Dorfman disease and Langerhans cell histiocytosis while also providing novel insights into gamma heavy chain disease. Notably, his clinical trials have introduced promising approaches such as low-dose cytarabine and novel immunomodulatory therapies, offering alternatives for conditions with limited treatments. Beyond publications, Dr. Long Chang demonstrates commitment to translational medicine by bridging molecular research with patient-centered care. Recognized by peers for his rigor, innovation, and leadership, he has progressed from Resident and Chief Resident to Attending Physician, reflecting both clinical expertise and academic excellence. With impactful contributions influencing practice worldwide, Dr. Long Chang exemplifies the qualities of a dedicated physician-scientist whose work continues to advance the frontiers of hematology.

Profile: Scopus

Featured Publications

  • Chang, L., Zhou, D. B., & Cao, X. X. (2023). Gamma heavy chain disease: A retrospective analysis of 6 cases. Orphanet Journal of Rare Diseases, 18(1), 77.

  • Chang, L., Qiao, B., Cai, H., et al. (2023). Clinical phenotypes, molecular analysis, and outcomes of patients with Rosai-Dorfman disease. Leukemia, 37(11), 2297–2300.

  • Chang, L., Lang, M., Lin, H., et al. (2024). Phase 2 study using low dose cytarabine for adult patients with newly diagnosed Langerhans cell histiocytosis. Leukemia, 38(4), 803–809.

  • Chang, L., Lang, M., Liu, T., et al. (2024). Lenalidomide and dexamethasone for Rosai-Dorfman disease: A single arm, single center, prospective phase 2 study. EClinicalMedicine, 73, 102685.

  • Chang, L., Cai, H. C., Lang, M., et al. (2024). Liver involvement with Langerhans cell histiocytosis in adults. The Oncologist. Advance online publication.

Zhiliang Xu | Medicine and Health Sciences | Best Researcher Award

Prof. Zhiliang Xu | Medicine and Health Sciences | Best Researcher Award

Wannan Medical College | China

Prof. Zhiliang Xu, affiliated with Wannan Medical College, Wuhu, China, is a distinguished molecular biologist and epigenetics researcher whose work focuses on histone ubiquitination, chromatin remodeling, and their implications in neurological disorders, cancer, gametogenesis, and cellular reprogramming. He earned his Ph.D. from the State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences in 2017. According to Scopus, Prof. Zhiliang Xu has authored 11 publications, which have been cited 34 times, and he holds an h-index of 4, demonstrating the impact of his research in the scientific community. His seminal studies elucidated the role of H2B ubiquitination in chromatin relaxation during meiosis and cellular reprogramming, published in journals such as Nucleic Acids Research (2016), Cell Proliferation (2021), and Reproduction (2017). His recent work on neuronal repair, gut-liver axis regulation in diabetes, and genomic approaches to thalassemia has been featured in FASEB Journal (2025), Annals of Hematology (2025), and Neuroscience Letters (2025). Prof. Zhiliang Xu leads multiple high-impact national and provincial research projects, serves as a peer reviewer for journals including Scientific Reports and Neurochemical Research, and evaluates theses for graduate and doctoral candidates. Recognized with the 2021 National Maternal and Child Health Science and Technology Award (First Prize), the 2022 Guangzhou High-level Talent Award, and the 2024 Outstanding Young Talent honor in Anhui Province, Prof. Zhiliang Xu continues to advance fundamental understanding of chromatin biology and epigenetic regulation, exemplifying excellence, mentorship, and translational scientific impact, making him an outstanding candidate for the Best Researcher Award.

Profile: Scopus | ORCID

Featured Publications

1. Shi, L., Yan, X., Xia, Y., Zhao, Y., Zhu, X., Li, Q., & Xu, Z. (2025). Beyond transfusions and transplants: Genomic innovations rewriting the narrative of thalassemia. Annals of Hematology.

2. Zhang, Y., Wang, J., Huang, S., Liu, M., Zhao, Y., Xu, Z., & Zhu, X. (2025). Electroacupuncture preconditioning alleviates cortical neuronal injury in cerebral ischemia-reperfusion by rebalancing HES1 and NF-κB expression. Neuroreport.

3. Yan, X., Shi, L., Zhu, X., Zhao, J., Zhao, Y., Luo, J., Li, Q., & Xu, Z. (2025). From microbial homeostasis to systemic pathogenesis: A narrative review on gut flora’s role in neuropsychiatric, metabolic, and cancer disorders. Journal of Inflammation Research.

4. Huang, S., Lu, Y., Fang, W., Huang, Y., Li, Q., & Xu, Z. (2025). Neurodegenerative diseases and neuroinflammation-induced apoptosis. Open Life Sciences.

5. Li, Q., Zhang, L., Sun, Y., Du, Z., Xu, S., Wang, X., Wei, S., Tao, Y., Li, B., Jiang, J., Di, G., Huang, Y., & Xu, Z. (2025). p53 modulates the gut-liver axis via PI3K/AKT/Wnt signaling pathways in type 2 diabetes. FASEB Journal.

6. Li, Q., Yan, X., Zhao, Y., Xu, Z., & Zhu, X. (2025). Paeonol mitigates chronic stress-induced amygdalar neuronal damage through glycogen synthase kinase-3β/calcineurin axis regulation of synaptic plasticity. Neuroreport.

7. Zhu, X., Zhang, Y., Yan, X., Zhao, Y., Shi, L., Sun, Z., Meng, K., Zong, Y., Li, Q., & Xu, Z. (2025). Paeonol facilitates the repair of neuronal damage in the mPFC caused by chronic stress via the Rho GTPases-cofilin1 signaling pathway. Neuroscience Letters, 138329.

Sezgin Gunes | Medicine and Health Sciences | Best Academic Researcher Award

Prof. Sezgin Gunes | Medicine and Health Sciences | Best Academic Researcher Award

Ondokuz Mayis University | Turkey

Prof. Sezgin Gunes is a renowned academic leader and medical researcher whose career has been defined by an unwavering commitment to advancing knowledge in medical biology and reproductive sciences. As Chair of the Department of Medical Biology at the Faculty of Medicine, Ondokuz Mayis University, she has led pioneering research in molecular medicine, andrology, and clinical genetics. Her scholarly journey reflects a distinguished blend of academic leadership, mentorship, and impactful contributions to scientific literature. Through international collaborations, high-impact publications, and mentorship of young researchers, Prof. Sezgin Gunes has established herself as one of the leading voices in reproductive health and molecular biology.

Professional Profile

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ORCID

Education

Prof. Sezgin Gunes holds a Bachelor of Science degree in Biological Sciences from Middle East Technical University, followed by a Master of Science and Doctor of Philosophy in Medical Biology from the Faculty of Medicine, Ondokuz Mayis University. Her solid academic foundation in biology and medical sciences enabled her to pursue a successful career as a researcher and educator. She further enhanced her expertise through a competitive research fellowship at the Cleveland Clinic in the United States, where she worked at the American Center of Reproductive Medicine and Andrology. This international training allowed her to engage with global leaders in reproductive health and to develop innovative perspectives on male infertility and molecular diagnostics. Her academic path demonstrates both intellectual depth and a consistent focus on bridging fundamental science with clinical application.

Experience

Prof. Sezgin Gunes has risen through the academic ranks with distinction, serving in multiple leadership and teaching roles at Ondokuz Mayis University. Beginning as a faculty member in Medical Biology, she progressed to leadership roles where she currently chairs the department while also contributing to the Graduate Institute’s Department of Multidisciplinary Molecular Medicine. Beyond her institutional roles, she has played an important part in mentoring both undergraduate and postgraduate students, supervising their research, and guiding them in scientific publishing. Her international engagements include mentoring summer internship programs at the Cleveland Clinic, where she inspired young researchers in reproductive medicine. She has also been actively involved in scientific project management, European Union projects, and advanced training in assisted reproductive techniques. Her career represents a combination of research excellence, administrative leadership, and dedication to academic mentorship.

Research Interests

The research contributions of Prof. Sezgin Gunes are focused on andrology, male infertility, and the molecular mechanisms underlying reproductive health. Her investigations explore sperm DNA fragmentation, chromatin quality, oxidative stress, gene expression, and cytogenetic alterations that contribute to male infertility. In addition, her work on epigenetics and urological malignancies has advanced understanding of how environmental, genetic, and molecular factors interact in reproductive dysfunctions and cancer development. She has explored the role of microRNAs, promoter methylation, and polymorphisms in idiopathic infertility, contributing critical insights into personalized medicine approaches. Her research is not only groundbreaking in the academic sense but also has important translational applications, influencing diagnostic tools and therapeutic strategies in clinical practice.

Awards and Recognition

Throughout her career, Prof. Sezgin Gunes has been recognized with numerous distinctions, fellowships, and certifications that reflect her dedication to advancing science and education. She has been honored with opportunities to conduct research at leading international institutions, gaining exposure to cutting-edge reproductive medicine technologies. Her professional development includes certifications in scientific project management, European Union project management, and advanced training in assisted reproduction. These achievements highlight her versatility as both a scientist and a leader. Her recognition is not limited to academic achievements but also extends to her role as a mentor, project leader, and collaborator in international research networks.

Publications

Prof. Sezgin Gunes has authored an impressive portfolio of publications in leading international journals, making significant contributions to reproductive medicine, molecular biology, and clinical genetics. Her widely cited works include:

  • Smoking and male infertility: an evidence-based review
    Journal: The World Journal of Men’s Health
    Published on: 2015
    Citation: 379

  • Effects of aging on the male reproductive system
    Journal: Journal of Assisted Reproduction and Genetics
    Published on: 2016
    Citation: 320

  • Spermatogenesis, DNA damage and DNA repair mechanisms in male infertility
    Journal: Reproductive Biomedicine Online
    Published on: 2015
    Citation: 275

  • The role of epigenetics in idiopathic male infertility
    Journal: Journal of Assisted Reproduction and Genetics
    Published on: 2016
    Citation: 167

  • Role of genetics and epigenetics in male infertility
    Journal: Andrologia
    Published on: 2021
    Citation: 159

  • Association of interleukin‐10 gene polymorphisms with severe generalized chronic periodontitis
    Journal: Journal of Periodontology
    Published on: 2007
    Citation: 104

  • Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility
    Journal: Rheumatology International
    Published on: 2008
    Citation: 100

Conclusion

Prof. Sezgin Gunes stands out as a visionary researcher, accomplished academic, and respected leader in medical biology and reproductive medicine. Her contributions to the understanding of male infertility, gene expression, cytogenetics, and epigenetics have had profound impact in both research and clinical contexts. With an outstanding record of scientific publications, international collaboration, and mentorship of future scientists, she represents the model of a globally engaged and impactful researcher. Her achievements and leadership make her an ideal candidate for the Best Academic Researcher Award, reflecting her dedication to advancing science and improving human health through innovative and meaningful research.