Xi’an No.9 Hospital | China

Prof. Qingbao Guo is a highly accomplished Associate Chief Physician in the Department of Neurosurgery at the Second Affiliated Hospital of the Air Force Medical University (formerly Tangdu Hospital), China. He specializes in cerebrovascular disorders, brain tumors, and functional neurosurgery, and is recognized for his excellence in the diagnosis and treatment of moyamoya disease and other complex neurological conditions.

Professional profile👤

ORCID

Scopus

Strengths for the Awards✨

1. Extensive Clinical Experience:

   • Over 20 years of progressive clinical practice in neurosurgery, including leadership as Associate Chief Physician at a top-tier military hospital.

   • Strong surgical expertise in cerebrovascular diseases, brain tumors, and functional neurosurgery, which are critical areas in modern neurosurgical practice.

2. Academic Qualifications & Research:

   • A recent Ph.D. in Neurosurgery (2021–2024) focused on moyamoya disease (MMD)—a rare but significant cerebrovascular disorder.

   • Earlier Master’s-level research on peripheral vascular diseases, showing continuity in vascular-focused research.

   • Mentorship under established experts (Professors Lian Duan and Yanzheng He), enhancing academic rigor.

3. Contribution to National Defense Health System:

   • His long-term service in military medical institutions (Air Force Medical University) underscores contributions to military medicine, a high-impact field with national importance.

4. Interdisciplinary Relevance:

   • His work bridges clinical practice and surgical innovation, especially in the surgical management of complex neurological diseases, offering translational value to both academic and applied medicine.

🎓 Education

Prof. Qingbao Guo began his academic journey with a Bachelor’s degree in Clinical Medicine from Yan’an University (1999–2004). He furthered his specialization with a Master’s degree in Surgery (2008–2011) from Southwest Medical University, under the supervision of Prof. Yanzheng He, where he focused on clinical approaches to peripheral vascular diseases. Most recently, he earned his Ph.D. in Neurosurgery (2021–2024) from the Chinese PLA Medical School, mentored by Prof. Lian Duan, with research concentrating on the pathogenesis and surgical management of moyamoya disease.

💼 Professional Experience

Prof. Qingbao Guo has an extensive and progressive professional background in neurosurgery. He is currently serving as an Associate Chief Physician at Tangdu Hospital since September 2012, where he has amassed advanced surgical experience in managing brain tumors, vascular pathologies, and functional neurosurgical disorders. Prior to this, he was an Attending Physician at the First Affiliated Hospital of Southwest Medical University (July 2011 – August 2012), where he handled numerous vascular cases. His medical career began as a Resident Physician at Shaanxi Sengong Hospital (July 2004 – August 2008).

🔬 Research Interests On Neuroscience

Prof. Qingbao Guo’s research focuses on the pathophysiology and surgical treatment of cerebrovascular diseases, particularly moyamoya disease, a rare but serious condition affecting intracranial arteries. He is also interested in neuro-oncology, vascular neurosurgery, and advancements in functional neurosurgical procedures, with a vision to bridge translational neuroscience and surgical innovation.

🏆 Awards & Nominations

Prof. Qingbao Guo has been acknowledged for his clinical excellence and academic contribution through multiple hospital-level and regional honors. He is a nominee for the [Insert Award Name Here, e.g., “Outstanding Neurosurgeon Researcher Award 2025”] in recognition of his pioneering work in moyamoya disease surgical treatment and his consistent commitment to patient-centered research and education.

📚 Publications

🔬 Genetic Associations and Polymorphisms

1. MTHFR Polymorphism and EDAS-induced Collateral Formation

   • [DOI: 10.3171/2024.1.JNS232121]
     Highlights the genetic influence (MTHFR) on surgical angiogenesis success post-EDAS in MMD patients.

2. RNF213 p.R4810K Variant and Unfavorable Outcomes in Pediatric EDAS

   • [DOI: 10.1155/2024/1844190]
     Strong linkage of the RNF213 mutation with poor long-term outcomes, particularly relevant in East Asian populations.

🧪 Biomarker and Multi-Omics Studies

3. Proteomic & Metabolomic Profiles in Pediatric MMD

   • [DOI: 10.2147/JIR.S471538]
     Identifies core disrupted pathways, potentially pointing toward new diagnostic or therapeutic targets.

4. Complement C3 Expression & Postoperative Vasculopathy

   • [DOI: 10.2147/JIR.S451538]
     Suggests inflammatory markers like C3 as predictors of vascular changes post-intervention.

🧠 Neuroimaging and Risk Stratification

5. MRI Vessel Wall Enhancement and MMD Outcomes

   • [DOI: 10.1007/S00330-023-10535-0]
     High-resolution MRI features were linked to clinical risk, potentially informing preoperative planning.

6. Nomograms for Predicting Rebleeding and Outcomes

   • [DOI: 10.3171/2024.2.JNS232744]
     Well-validated clinical tools that integrate genetics and clinical features for long-term prognosis.

🧬 Pathophysiology and Comorbid Disease Connections

7. Transcriptomics in MMD and SLE Crosstalk

   • [DOI: 10.3389/FIMMU.2024.1456392]
     A novel systems biology approach to uncover common pathways between MMD and autoimmune diseases like SLE.

8. ZEB2 and Brain Microvascular Dysfunction Post-ICH

   • [DOI: 10.1080/15384101.2021.1959702]
     Delves into molecular mechanisms of endothelial dysfunction, bridging stroke and hemorrhage pathology.

📉 Risk Factors in Pediatric and Elderly Cohorts

9. Preoperative Infarction & Pediatric Risk Factors

   • [DOI: 10.1007/S12975-023-01167-Z]
     Targeted focus on predictive markers in vulnerable pediatric populations.

10. Outcomes in Elderly Post-Conservative vs. EDAS Treatment

• [DOI: 10.3171/2023.7.JNS231060]
  Offers insights into age-specific management strategies and long-term care plans.

🔚 Conclusion

Prof. Qingbao Guo stands out as a dedicated neurosurgeon, educator, and researcher, committed to transforming patient outcomes through clinical expertise and scientific inquiry. His extensive training, hands-on experience, and impactful research make him a compelling candidate for any award celebrating excellence in medical and surgical innovation.