Professor | University of Utah | United States
Dr. Christopher A. Reilly is a renowned pharmacologist and toxicologist at the University of Utah. As a professor and director of the Center for Human Toxicology, he has made significant contributions to understanding toxicological mechanisms, particularly involving TRP channels and environmental pollutants. With an extensive career in research, teaching, and mentoring, Dr. Reilly is a leader in the field, dedicated to advancing pharmacological sciences and improving public health.
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Strengths for the Awards
- Academic and Research Excellence:
Dr. Reilly has a distinguished academic background with a Ph.D. in Toxicology and over 25 years of research experience. His tenure as a professor and leadership roles, such as Director of the Center for Human Toxicology, underscore his expertise and impact in his field.
- Extensive Publication and Research Funding:
Dr. Reilly has secured substantial research funding from prestigious institutions, including NIH, DOD, and NSF. His work covers critical topics such as air pollution, pharmacokinetics, TRP channels, and toxicology. His projects have garnered over $10 million in research funding, demonstrating his ability to lead impactful and high-value research.
- Recognized Contributions:
He has received multiple honors, including the Gordon Research Conference Travel Awards and Colgate-Palmolive Post-Doctoral Fellowship, reflecting the significance of his contributions to toxicology. His publications have been featured in high-impact journals, with several being highlighted as “Manuscript Highlights” and “Cover Articles.”
- Mentorship and Academic Service:
Dr. Reilly has mentored numerous students and fellows, several of whom have received significant awards and fellowships. He also contributes to academic governance, serving on multiple committees, including search committees, graduate councils, and retention and promotion committees.
Education 🎓
Dr. Reilly’s academic journey began at the University of Utah, where he earned a B.S. in Biology with emphases in Biochemistry, Molecular Biology, Ecology, and Evolution, and a minor in Chemistry (1994). He then pursued his Ph.D. in Toxicology at Utah State University (1999). Following his doctorate, he completed a prestigious postdoctoral fellowship in Pharmacology and Toxicology at the University of Utah, under the mentorship of Dr. Dennis J. Crouch and Dr. Garold S. Yost.
Experience 🏢
Dr. Reilly has built a distinguished career at the University of Utah, where he currently serves as Professor and Director of the Center for Human Toxicology. Since joining in 1999 as a postdoctoral fellow, he has held numerous roles, including Associate Director and Research Assistant Professor. His career highlights include mentoring in the Pediatric Clinical Pharmacology Program and conducting pioneering research in toxicology and pharmacology.
Research Interests Toxicology 🔬
Dr. Reilly’s research focuses on the toxicological mechanisms mediated by TRP channels, the impact of air pollution on health, and pharmacokinetics. His work delves into the interface of environmental toxicants and human physiology, with a particular emphasis on understanding molecular pathways for therapeutic interventions.
Awards and Honors 🏅
Dr. Reilly has received numerous accolades, including the 2001 Colgate-Palmolive Post-Doctoral Fellowship and the Society of Toxicology’s Domestic ToxScholar Visitor recognition in 2020-2021. He was also inducted as a Fellow of the Academy of Toxicological Sciences in 2023. His research publications have frequently been highlighted as “Featured Articles” or “Cover Articles,” reflecting their impact on the scientific community.
Publications 📚
- Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors
Authors: CA Reilly, JL Taylor, DL Lanza, BA Carr, DJ Crouch, GS Yost
Year: 2003
Citations: 236
- Quantitative analysis of capsaicinoids in fresh peppers, oleoresin capsicum and pepper spray products
Authors: CA Reilly, DJ Crouch, GS Yost
Year: 2001
Citations: 194
- Peroxidase substrates stimulate the oxidation of hydralazine to metabolites which cause single-strand breaks in DNA
Authors: CA Reilly, SD Aust
Year: 1997
Citations: 189
- Determination of capsaicin, dihydrocapsaicin, and nonivamide in self-defense weapons by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry
Authors: CA Reilly, DJ Crouch, GS Yost, AA Fatah
Year: 2001
Citations: 179
- Human lung epithelial cells express a functional cold-sensing TRPM8 variant
Authors: AS Sabnis, M Shadid, GS Yost, CA Reilly
Year: 2008
Citations: 173
- A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda
Authors: JD Phillips, HA Bergonia, CA Reilly, MR Franklin, JP Kushner
Year: 2007
Citations: 172
- Metabolism of capsaicin by cytochrome P450 produces novel dehydrogenated metabolites and decreases cytotoxicity to lung and liver cells
Authors: CA Reilly, WJ Ehlhardt, DA Jackson, P Kulanthaivel, AE Mutlib, RJ Espina, …
Year: 2003
Citations: 151
- Measurement of lipid peroxidation
Authors: CA Reilly, SD Aust
Year: 1999
Citations: 147
- Metabolism of capsaicinoids by P450 enzymes: a review of recent findings on reaction mechanisms, bio-activation, and detoxification processes
Authors: CA Reilly, GS Yost
Year: 2006
Citations: 123
- Increased transcription of cytokine genes in human lung epithelial cells through activation of a TRPM8 variant by cold temperatures
Authors: AS Sabnis, CA Reilly, JM Veranth, GS Yost
Year: 2008
Citations: 114
Conclusion ✨
Dr. Christopher A. Reilly exemplifies leadership and innovation in toxicology research, education, and mentorship. His dedication to unraveling the complexities of toxicological mechanisms and environmental health impacts has made a lasting impact in academia and beyond. As a mentor, researcher, and professor, Dr. Reilly continues to inspire the next generation of scientists and contribute significantly to public health initiatives.
