Prof. Dr. Leng Chee Chang | Pharmacology | Research Excellence Award
University of Hawaii at Hilo | United States
Prof. Dr. Leng Chee Chang is a natural products chemist whose work focuses on the isolation, characterization, and biological evaluation of bioactive compounds from medicinal plants, marine algae, and microbes with applications in cancer chemoprevention, chemotherapeutics, and antimicrobial discovery. According to Scopus-indexed records, she has authored 73 publications, which have been cited 2,567 times, reflecting a substantial global research impact. Her h-index of 28 highlights consistent scholarly influence and sustained citation performance across her body of work. Dr. Chang’s research has appeared in high-impact journals such as Organic Letters, Journal of Natural Products, Molecules, and ACS Omega, and encompasses multidisciplinary collaborations in pharmacognosy, medicinal chemistry, and pharmacology. Her work has contributed to the discovery of novel natural products with therapeutic potential.
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Featured Publications
A New Trichlorinated Xanthone and Compounds Isolated from Cladonia skottsbergii with Antimicrobial Properties
– Rositzki MJ, Raksat A, Simmons CJ, Smith C, Reverend Danette V. Choi, Wongwiwatthananukit S, Chang LC · Pharmaceuticals, 2026
Bioactive Constituents from the Edible Seaweed Halymenia hawaiiana (Rhodophyta)
– Raksat A, Atanu MSH, McDermimid KJ, Wall MW, Chang BL, Wongwiwatthananukit S, Chang LC · Pharmaceutical Biology, 2025
Bioactive Compounds from Dodonaea viscosa Flowers: Potent Antibacterial and Antiproliferative Effects in Breast Cancer Cells
– Raksat A, Yee D, Gi YJ, Wongwiwatthananukit S, Chang LK, Kaawaloa P, Wall MW, Chang LC · Molecules, 2025 (IF 4.2)
Biologically Active Withanolides from Physalis peruviana L.
– Sang-Ngern M, Fukuchi A, Kondratyuk TP, Park E-J, Simmons CJ, Wall MW, Lorch SE, Pezzuto JM, Chang LC · Pharmaceutical Biology, 2025
Vernonolide A, a Sesquiterpene Lactone with a Unique Carbon Skeleton from Vernonia cinerea
– Zhang M, Kondratyuk TP, Cao S, Li M, Songsak T, Wongwiwatthananukit S, Cai Y-S, Chang LC · Organic Letters, 2025 (IF 4.9)
