The Third Affiliated Hospital of Southern Medical University | China
Dr. Dong Guo is a dedicated and emerging scholar in the field of Orthopaedics, currently pursuing his Ph.D. at Southern Medical University under the guidance of Dr. Denghui Xie. With a solid background in clinical medicine, Dong Guo has quickly progressed through rigorous academic training and impactful research roles. He brings a multidisciplinary approach to medical science, integrating knowledge from cellular biology, nanotechnology, and regenerative medicine. His contributions have already begun to shape promising directions in rheumatoid arthritis and osteoarthritis treatment.
Professional profile👤
ORCID
Scopus
Strengths for the Awards✨
Dong Guo demonstrates exceptional potential and performance in biomedical research, particularly in orthopaedics and inflammatory joint diseases such as rheumatoid arthritis, osteoarthritis, and osteoporosis. His strong educational foundation—holding a Bachelor in Clinical Medicine, a Master’s, and now pursuing a Ph.D. at Southern Medical University—provides a solid platform for advanced research. His research productivity is evident through multiple Q1 journal publications with high impact factors:
-
Bone Research (IF: 13.362, cited by 51)
-
Bioactive Materials (IF: 18.0)
-
Theranostics (IF: 12.4)
-
Journal of Nanobiotechnology (IF: 10.6)
🎓 Education
Dr. Dong Guo commenced his academic journey with a Bachelor’s degree in Clinical Medicine (2013–2018) from Jiangsu University, followed by a Master’s degree in Orthopaedics (2018–2021) under Dr. Daozhang Cai at Southern Medical University. He is currently enrolled as a Ph.D. candidate in Orthopaedics (2022–present) under the mentorship of Dr. Denghui Xie at the same institution, focusing on innovative therapies for chronic musculoskeletal disorders.
🏥 Experience
From July 2021 to September 2022, Dong Guo served as a Research Assistant at The Third Affiliated Hospital of Southern Medical University, where he actively contributed to experimental research and clinical translational work in orthopaedics and inflammatory diseases. His academic visibility was highlighted through oral presentations at prestigious national forums, including the Chinese Sport Medical Doctor Association (2021 & 2024) and the Guangdong Sport Medical Doctor Association (2022).
Dong Guo’s research is driven by a passion to decode the cellular and molecular mechanisms underlying joint diseases. His primary interests include Rheumatoid Arthritis, Osteoarthritis, Osteoporosis, and Senescence, with focused work on osteoclast biology, mitochondrial biogenesis, and nanotherapeutic interventions. He is also exploring innovative delivery mechanisms for gene therapy in degenerative diseases.
🏆 Awards
Dong Guo has received several accolades for his scholarly excellence and research innovation:
-
National Scholarships in 2022 and 2024
-
Best Oral Presentation Award at the 1st BMEMat-Advanced Materials Joint Symposium (2024)
-
Selected Oral Presentation Award at the Guangdong-Hong Kong-Macao Greater Bay Area Orthopedic Postgraduate Academic Forum (2024)
-
Excellent Manuscript Award by the Chinese Sport Medical Doctor Association (2021)
-
Second Prize in Thesis Competition at the Guangdong Postgraduate Academic Forum (2023)
-
High-Quality Experimental Works recognition at Southern Medical University (2022)
đź“š Publications
Dong Guo has published several high-impact research articles in prestigious journals:
-
FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritis, Bone Research, 2022. Cited by: 51
-
A Nanoplatform Reprograms Hypoxia M1 Macrophage by Interrupting Adverse Feedback Loop for Synergistic Rheumatoid Arthritis Therapy, Bioactive Materials, 2024.
-
Photoreceptor-targeted extracellular vesicles-mediated delivery of Cul7 siRNA for retinal degeneration therapy, Theranostics, 2024.
-
Polypyrrole-ferric phosphate-methotrexate nanoparticles enhance apoptosis/ferroptosis of M1 macrophages via autophagy blockage for rheumatoid arthritis treatment, Journal of Nanobiotechnology, 2025.
-
Rspo2 exacerbates rheumatoid arthritis by targeting aggressive phenotype of fibroblast-like synoviocytes and disrupting chondrocyte homeostasis via Wnt/β-catenin pathway, Arthritis Research & Therapy, 2023.
🧾 Conclusion
Dong Guo exemplifies the qualities of a rising star in biomedical and clinical research. His integrated expertise in orthopaedics, nanotherapy, and molecular signaling, paired with his recognized contributions to high-impact publications and presentations, make him a worthy nominee for any Best Researcher Award. With a promising trajectory and a passion for scientific discovery, Dong Guo is poised to lead innovative advancements in musculoskeletal disease therapy. 🌟
