Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Published on by Forensic Scientist

Prof. Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Tehran Medical Sciences, Islamic Azad University | Iran

Professor Mehrdad Hashemi is a renowned scholar in Molecular and Medical Genetics whose pioneering research has made transformative contributions to predictive, preventive, and personalized medicine. His scientific work focuses on the discovery of diagnostic and therapeutic biomarkers particularly non-coding RNAs (lncRNAs and miRNAs) with profound implications for early disease detection, molecular targeting, and precision therapy. Prof. Mehrdad Hashemi has authored 372 peer-reviewed publications indexed in Scopus, accumulating over 6,826 citations from 6,242 documents, and achieving a remarkable h-index of 41. His research portfolio includes 299 ISI-indexed papers, 342 Scopus-indexed papers, and 258 PubMed articles, encompassing 119 Q1 and 82 Q2 journals. He has led or completed 14 major research projects, contributed to 95 industrial and academic collaborations, and maintained 110 international research partnerships with leading institutions across the USA, UK, Canada, China, Germany, Australia, and beyond. His scholarly output also includes 3 internationally published books and 1 patent. Ranked among the World’s Top 1% and 2% Scientists in both ESI (2024) and Stanford (2024–2025) global rankings, Prof. Mehrdad Hashemi’s groundbreaking studies on exosomes, nanomedicine, gene regulation, and cancer therapeutics have advanced global understanding of disease mechanisms and innovative treatment modalities. He also contributes extensively as an editorial board member, peer reviewer, and thought leader in the field of molecular diagnostics and translational genetics.

Profiles: Scopus | Google Scholar | ORCID | Staff Page

Featured Publications

  • Paskeh, M. D. A., Entezari, M., Mirzaei, S., Zabolian, A., Saleki, H., Naghdi, M. J., … & Hashemi, M. (2022). Emerging role of exosomes in cancer progression and tumor microenvironment remodeling. Journal of Hematology & Oncology, 15(1), 83. https://doi.org/10.1186/s13045-022-01296-0

  • Bolhassani, A., Javanzad, S., Saleh, T., Hashemi, M., Aghasadeghi, M. R., … & Sadat, S. M. (2014). Polymeric nanoparticles: potent vectors for vaccine delivery targeting cancer and infectious diseases. Human Vaccines & Immunotherapeutics, 10(2), 321–332. https://doi.org/10.4161/hv.26796

  • Entezari, M., Hashemi, D., Taheriazam, A., Zabolian, A., Mohammadi, S., … & Hashemi, M. (2022). AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation. Biomedicine & Pharmacotherapy, 146, 112563. https://doi.org/10.1016/j.biopha.2021.112563

  • Hashemi, M., Moosavi, M. S., Abed, H. M., Dehghani, M., Aalipour, M., Heydari, E. A., … & Mirzaei, S. (2022). Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy. Pharmacological Research, 184, 106418. https://doi.org/10.1016/j.phrs.2022.106418

  • Sadrkhanloo, M., Entezari, M., Orouei, S., Ghollasi, M., Rezaei, S., Hejazi, E. S., … & Hashemi, M. (2022). STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response. Pharmacological Research, 182, 106311. https://doi.org/10.1016/j.phrs.2022.106311

Xiaowen Mao | Medicine and Health Sciences | Best Researcher Award

Published on by Forensic Scientist

Assist. Prof. Dr. Xiaowen Mao | Medicine and Health Sciences | Best Researcher Award

University of Macau | Macau

Dr. Xiaowen Mao, M.D., Ph.D., is an Assistant Professor at the State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, where she leads translational research on cancer biology, immunotherapy, and tumor microenvironment modulation. She earned her Ph.D. in Biomedical Sciences from the University of Hong Kong and her B.Sc. in Clinical Medicine from Shanghai Jiao Tong University, China. Her research focuses on extracellular vesicles, immune homeostasis, metabolic reprogramming in tumors, and hepatocellular carcinoma metastasis, integrating molecular, cellular, and translational approaches. Dr. Xiaowen Mao has led several high-impact projects as principal investigator, funded by the Health and Medical Research Fund, National Natural Science Foundation Young Scientist Fund, and FDCT Innovation and Technology Promotion. Her significant contributions include the development of broadly potent neutralizing antibodies targeting Nidogen 1 to inhibit tumor growth, elucidation of extracellular vesicle-mediated metabolic reprogramming in tumors, and advances in dendritic cell vaccine strategies. She holds a U.S. patent on Nidogen 1 as a diagnostic and therapeutic target for hepatocellular carcinoma, serves as Guest Editor for Frontiers in Endocrinology, and is an ad-hoc reviewer for multiple high-impact journals. According to Scopus, she has 31 publications, 1,114 citations by 1,010 documents, and an h-index of 20. Dr. Xiaowen Mao’s work bridges fundamental research and clinical translation, delivering innovative therapies and advancing precision medicine in oncology, while demonstrating a profound impact on cancer biology, immunotherapy, and translational research.

Profile: Scopus

Featured Publications

  • Xue, T. M., Yeung, C. L. S., Mao, X. W., Tey, S. K., Lo, K. W., Tang, H. N., Yun, J. P., & Yam, J. W. P. (2025). Development of a broadly potent neutralizing antibody targeting Nidogen 1 effectively inhibits cancer growth and metastasis in preclinical tumor models. Journal of Translational Internal Medicine. https://doi.org/10.1515/jtim-2025-0008

  • Xia, L., Li, C. G., Zhao, J., Sun, Q. C., & Mao, X. W.* (2025). Rebalancing immune homeostasis in combating disease: The impact of medicine food homology plants and gut microbiome. Phytomedicine, 136, 156150. https://doi.org/10.1016/j.phymed.2025.156150

  • Chen, Z., Yam, J. W. P., & Mao, X. W.* (2024). The multifaceted roles of small extracellular vesicles in metabolic reprogramming in the tumor microenvironments. Proteomics, e2300021. https://doi.org/10.1002/pmic.202300021

  • Lee, K. W., Yam, J. W. P., & Mao, X. W.* (2023). Dendritic cell vaccines: A shift from conventional approach to new generations. Cells, 12(2147). https://doi.org/10.3390/cells12172147

  • Li, S., Delvecchio, M., Ramkumar, K., Mao, X. W., Sun, X. D., & Guo, S. Z. (2023). Editorial: Clinical and genetic determinants of diabetes and complications. Frontiers in Endocrinology.