Zerrin Kutlu | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

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Assoc. Prof. Dr. Zerrin Kutlu | Biochemistry, Genetics and Molecular Biology | Research Excellence Award

Ataturk University | Turkey

Assoc. Prof. Dr. Zerrin Kutlu is a leading biochemist whose research focuses on oxidative stress, endoplasmic reticulum (ER) stress, inflammation, and diabetes-related complications, with an emphasis on elucidating molecular mechanisms underlying organ injury and cardiometabolic disorders. Her work spans ischemic heart injury, sepsis-induced organ damage, osteoporosis, and metabolic disease models, highlighting the interplay between oxidative stress and cellular dysfunction. Dr. Zerrin Kutlu has authored 15 Scopus-indexed publications, cited 211 times, with an h-index of 9, reflecting the impact and recognition of her research in the scientific community. She has contributed book chapters and served extensively as a peer reviewer and editorial board member for high-impact journals. Her pioneering studies on avasopasem manganese as a superoxide dismutase mimetic, alongside investigations of ATE1 enzyme biology, have provided novel insights into therapeutic strategies for diabetes, cardiovascular disease, and neurodegenerative disorders. She has advanced translational research through nanotechnology-based drug delivery systems, phenolic compound-loaded nanoparticles, and bioactive natural molecules, demonstrating the therapeutic potential of antioxidant and cytoprotective agents. In collaboration with industry and interdisciplinary teams, Dr. Zerrin Kutlu has developed boron-based bioactive compounds for dermo cosmetic and UV-protective applications, supported by TÜBİTAK-funded projects. Her portfolio includes multiple patents, international publications, and leadership in multi-center experimental studies, underscoring her commitment to innovation and scientific excellence. Through these contributions, Dr. Zerrin Kutlu has significantly advanced understanding of redox biology, ER stress modulation, and translational pharmacology, establishing herself as a recognized leader in biomedical research and therapeutic innovation.

Profiles: Scopus | Google Scholar | ORCID | ResearchGate | LinkedIn

Featured Publications

  • Dumlu, F. A., Aydin, T., Odabasoglu, F., Berktas, O. A., Kutlu, Z., Erol, H. S., … (2019). Anti-inflammatory and antioxidant properties of jervine, a steroidal alkaloid from rhizomes of Veratrum album. Phytomedicine, 55, 191–199.

  • Koc, K., Geyikoglu, F., Cakmak, O., Koca, A., Kutlu, Z., Aysin, F., Yilmaz, A., … (2021). The targets of β-sitosterol as a novel therapeutic against cardio-renal complications in acute renal ischemia/reperfusion damage. Naunyn-Schmiedeberg’s Archives of Pharmacology, 394(3), 469–479.

  • Karaoğlan, E. S., Albayrak, A., Kutlu, Z., & Bayır, Y. (2018). Gastroprotective and antioxidant effects of Eremurus spectabilis Bieb. methanol extract and its isolated component isoorientin on indomethacin-induced gastric damage. Acta Cirúrgica Brasileira, 33, 609–618.

  • Akpinar, E., Kutlu, Z., Kose, D., Aydin, P., Tavaci, T., Bayraktutan, Z., & Yuksel, T. N. (2022). Protective effects of idebenone against sepsis-induced acute lung damage. Journal of Investigative Surgery, 35(3), 560–568.

  • Kutlu, Z., Celik, M., Bilen, A., Halıcı, Z., Yıldırım, S., Karabulut, S., & Karakaya, S. (2020). Effects of umbelliferone isolated from the Ferulago pauciradiata Boiss. & Heldr. plant on cecal ligation and puncture-induced sepsis model in rats. Biomedicine & Pharmacotherapy, 127, 110206.

Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

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Prof. Mehrdad Hashemi | Biochemistry, Genetics and Molecular Biology | Best Researcher Award

Tehran Medical Sciences, Islamic Azad University | Iran

Professor Mehrdad Hashemi is a renowned scholar in Molecular and Medical Genetics whose pioneering research has made transformative contributions to predictive, preventive, and personalized medicine. His scientific work focuses on the discovery of diagnostic and therapeutic biomarkers particularly non-coding RNAs (lncRNAs and miRNAs) with profound implications for early disease detection, molecular targeting, and precision therapy. Prof. Mehrdad Hashemi has authored 372 peer-reviewed publications indexed in Scopus, accumulating over 6,826 citations from 6,242 documents, and achieving a remarkable h-index of 41. His research portfolio includes 299 ISI-indexed papers, 342 Scopus-indexed papers, and 258 PubMed articles, encompassing 119 Q1 and 82 Q2 journals. He has led or completed 14 major research projects, contributed to 95 industrial and academic collaborations, and maintained 110 international research partnerships with leading institutions across the USA, UK, Canada, China, Germany, Australia, and beyond. His scholarly output also includes 3 internationally published books and 1 patent. Ranked among the World’s Top 1% and 2% Scientists in both ESI (2024) and Stanford (2024–2025) global rankings, Prof. Mehrdad Hashemi’s groundbreaking studies on exosomes, nanomedicine, gene regulation, and cancer therapeutics have advanced global understanding of disease mechanisms and innovative treatment modalities. He also contributes extensively as an editorial board member, peer reviewer, and thought leader in the field of molecular diagnostics and translational genetics.

Profiles: Scopus | Google Scholar | ORCID | Staff Page

Featured Publications

  • Paskeh, M. D. A., Entezari, M., Mirzaei, S., Zabolian, A., Saleki, H., Naghdi, M. J., … & Hashemi, M. (2022). Emerging role of exosomes in cancer progression and tumor microenvironment remodeling. Journal of Hematology & Oncology, 15(1), 83. https://doi.org/10.1186/s13045-022-01296-0

  • Bolhassani, A., Javanzad, S., Saleh, T., Hashemi, M., Aghasadeghi, M. R., … & Sadat, S. M. (2014). Polymeric nanoparticles: potent vectors for vaccine delivery targeting cancer and infectious diseases. Human Vaccines & Immunotherapeutics, 10(2), 321–332. https://doi.org/10.4161/hv.26796

  • Entezari, M., Hashemi, D., Taheriazam, A., Zabolian, A., Mohammadi, S., … & Hashemi, M. (2022). AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation. Biomedicine & Pharmacotherapy, 146, 112563. https://doi.org/10.1016/j.biopha.2021.112563

  • Hashemi, M., Moosavi, M. S., Abed, H. M., Dehghani, M., Aalipour, M., Heydari, E. A., … & Mirzaei, S. (2022). Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy. Pharmacological Research, 184, 106418. https://doi.org/10.1016/j.phrs.2022.106418

  • Sadrkhanloo, M., Entezari, M., Orouei, S., Ghollasi, M., Rezaei, S., Hejazi, E. S., … & Hashemi, M. (2022). STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response. Pharmacological Research, 182, 106311. https://doi.org/10.1016/j.phrs.2022.106311