Dr. Giuseppe Federighi | Medicine and Health Sciences | Research Excellence Award

University of Pisa | Italy

Dr. Giuseppe Federighi is a neuroscientist and molecular biologist whose research focuses on gene expression regulation, neurovascular physiology, oxidative stress, and experimental hypertension. His work integrates molecular neuroscience with functional and behavioral approaches in animal models to investigate mechanisms underlying neuroprotection, cerebrovascular regulation, and metabolic modulation. He has made notable contributions to studies on acetyl-L-carnitine, antioxidant interventions, mandibular extension–induced hypotension, and cerebral microcirculation. According to Scopus, he has authored 19 peer-reviewed publications, received 153 citations, and holds an h-index of 7. His research outputs are published in high-visibility journals such as Molecular Neurobiology, PLoS One, Scientific Reports, and Frontiers in Physiology.

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Featured Publications


Physical exercise improves total antioxidant capacity and gene expression in rat hippocampal tissue

– F. Franzoni, G. Federighi, J. Fusi, et al. · Archives italiennes de biologie, 2017 · Cited by 38


Modulation of Myelin Basic Protein Gene Expression by Acetyl-l-Carnitine

– G. Traina, G. Federighi, M. Macchi, et al. · Molecular Neurobiology, 2011 · Cited by 27


Cytoprotective Effect of Acetyl-l-Carnitine Evidenced by Analysis of Gene Expression in the Rat Brain

– G. Traina, G. Federighi, M. Brunelli, R. Scuri · Molecular Neurobiology, 2009 · Cited by 25


Up-regulation of kinesin light-chain 1 gene expression by acetyl-L-carnitine: therapeutic possibility in Alzheimer’s disease

– G. Traina, G. Federighi, M. Brunelli · Neurochemistry International, 2008 · Cited by 24


Modulation of gene expression in contextual fear conditioning in the rat

– G. Federighi, G. Traina, M. Macchi, et al. · PLoS One, 2013 · Cited by 17 
Giuseppe Federighi | Medicine and Health Sciences | Research Excellence Award

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